D-赤藓糖-4-磷酸钠
D-赤藓糖-4-磷酸钠结构式
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常用名 | D-赤藓糖-4-磷酸钠 | 英文名 | D-Erythrose 4-phosphate sodium |
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| CAS号 | 103302-15-4 | 分子量 | 222.06600 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C4H8NaO7P | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Gas Chromatography-Quadrupole Time-of-Flight Mass Spectrometry-Based Determination of Isotopologue and Tandem Mass Isotopomer Fractions of Primary Metabolites for (13)C-Metabolic Flux Analysis.
Anal. Chem. 87 , 11792-802, (2015) For the first time an analytical work flow based on accurate mass gas chromatography-quadrupole time-of-flight mass spectrometry (GC-QTOFMS) with chemical ionization for analysis providing a comprehensive picture of (13)C distribution along the primary metabo... |
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Poisoning pyridoxal 5-phosphate-dependent enzymes: a new strategy to target the malaria parasite Plasmodium falciparum.
PLoS ONE 4(2) , e4406, (2009) The human malaria parasite Plasmodium falciparum is able to synthesize de novo pyridoxal 5-phosphate (PLP), a crucial cofactor, during erythrocytic schizogony. However, the parasite possesses additionally a pyridoxine/pyridoxal kinase (PdxK) to activate B6 vi... |
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Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum.
Biochem. J. 449(1) , 175-87, (2013) Malaria tropica is a devastating infectious disease caused by Plasmodium falciparum. This parasite synthesizes vitamin B6 de novo via the PLP (pyridoxal 5'-phosphate) synthase enzymatic complex consisting of PfPdx1 and PfPdx2 proteins. Biosynthesis of PLP is ... |
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Synthesis and evaluation of dual site inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.
Bioorg. Med. Chem. Lett. 21 , 5092-5097, (2011) 3-Deoxy-d-arabino-heptulosonate 7-phosphate (DAH7P) synthase catalyses the first step of the shikimate pathway for the biosynthesis of aromatic compounds. Enzymes of this pathway have been identified as potential targets for drug design. The reaction catalyse... |
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Cloning and heterologous overexpression of threegapgenes encoding different glyceraldehyde-3-phosphate dehydrogenases from the plant pathogenic bacteriumPseudomonas syringaepv. tomato strain DC3000
Protein Expr. Purif. 89(2) , 146-55, (2013) Highlights ► Genome sequence analyses revealed the presence in Pseudomonas syringae of 3 paralogous gap genes. ► The three gap genes were one-step cloned with a His-Tag in pET21a vector. ► Effect of alternatives carbon sources on the overexpression was studie... |
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Modular engineering of L-tyrosine production in Escherichia coli.
Appl. Environ. Microbiol. 78(1) , 89-98, (2012) Efficient biosynthesis of L-tyrosine from glucose is necessary to make biological production economically viable. To this end, we designed and constructed a modular biosynthetic pathway for L-tyrosine production in E. coli MG1655 by encoding the enzymes for c... |
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Metabolic engineering for microbial production of aromatic amino acids and derived compounds.
Metab. Eng. 3(4) , 289-300, (2001) Metabolic engineering to design and construct microorganisms suitable for the production of aromatic amino acids and derivatives thereof requires control of a complicated network of metabolic reactions that partly act in parallel and frequently are in rapid e... |
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Directed evolution of 2-keto-3-deoxy-6-phosphogalactonate aldolase to replace 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthase.
J. Am. Chem. Soc. 129 , 6130-6139, (2007) Directed evolution of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) aldolase for microbial synthesis of shikimate pathway products provides an alternate strategy to circumvent the competition for phosphoenolpyruvate between 3-deoxy-D-arabino-heptulosonic acid ... |
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Characterization of a recombinant type II 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Helicobacter pylori.
Biochem. J. 390 , 223-230, (2005) DAH7P (3-Deoxy-D-arabino-heptulosonate 7-phosphate) synthase catalyses the condensation reaction between phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) as the first committed step in the biosynthesis of aromatic compounds in plants and micro-orga... |
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The shikimate pathway in apicomplexan parasites: implications for drug development.
Front. Biosci. (Landmark Ed.) 18 , 944-69, (2013) The shikimate pathway provides basic building blocks for a variety of aromatic compounds including aromatic amino acids, ubiquinone, folate and compounds of the secondary metabolism. The seven enzymatic reactions of the pathway lead to the generation of chori... |