亚麻木酚素
亚麻木酚素结构式
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常用名 | 亚麻木酚素 | 英文名 | Secoisolariciresinol Diglucoside |
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| CAS号 | 148244-82-0 | 分子量 | 722.73 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 989.2±65.0 °C at 760 mmHg | |
| 分子式 | C32H50O18 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 552.0±34.3 °C |
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Further studies on a human intestinal bacterium Ruminococcus sp. END-1 for transformation of plant lignans to mammalian lignans.
J. Agric. Food Chem. 57(16) , 7537-42, (2009) A human intestinal bacterium Ruminococcus (R.) sp. END-1 capable of oxidizing (-)-enterodiol to (-)-enterolactone, enantioselectively, was further investigated from the perspective of transformation of plant lignans to mammalian lignans; A cell-free extract o... |
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Production of secoisolariciresinol from defatted flaxseed by bacterial biotransformation.
J. Appl. Microbiol. 113(6) , 1352-61, (2012) Secoisolariciresinol (SECO) is increasingly recognized for potential clinical application because of its preventive effects against breast and colon cancers, atherosclerosis and diabetes, and its production through biotransformation has been attempted. Howeve... |
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Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells.
J. Nutr. 142 , 1798-1805, (2012) Dietary lignans show some promising health benefits, but little is known about their fate and activities in the small intestine. The purpose of this study was thus to investigate whether plant lignans are taken up by intestinal cells and modulate the intestin... |
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Effects of the flaxseed lignans secoisolariciresinol diglucoside and its aglycone on serum and hepatic lipids in hyperlipidaemic rats.
Br. J. Nutr. 102(3) , 361-9, (2009) The present study involved a comparative analysis of the effects of purified flaxseed lignans, secoisolariciresinol diglucoside (SDG) and its aglycone metabolite (SECO), in hyperlipidaemic rats. For hypercholesterolaemia, female Wistars (six rats per group) w... |
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Effect of flaxseed lignans added to milk or fed to cows on oxidative degradation of dairy beverages enriched with polyunsaturated fatty acids.
J. Dairy Res. 78(1) , 111-7, (2011) Nutritional value is a priority in new product development. Using vegetable or marine oils, rich in polyunsaturated fatty acids, in dairy beverage formulations is an option to provide the consumers with healthier products. However, these formulations are pron... |
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Evaluation of the efficacy of flaxseed meal and flaxseed extract in reducing menopausal symptoms.
J. Med. Food 15(9) , 840-5, (2012) The objective of this study was to evaluate the efficacy of flaxseed meal and flaxseed extract in reducing climacteric symptoms of menopausal women. Ninety menopausal women were randomly distributed into three study groups: group I received 1 g per day of fla... |
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Cytostatic inhibition of cancer cell growth by lignan secoisolariciresinol diglucoside.
Nutr. Res. 30(11) , 762-9, (2010) Our previous study demonstrated that lignan metabolites enterolactone and enterodiol inhibited colonic cancer cell growth by inducing cell cycle arrest and apoptosis. However, the dietary lignans are naturally present as glycoside precursors, such as secoisol... |
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Natural products in regression and slowing of progression of atherosclerosis.
Curr. Pharm. Biotechnol. 11(8) , 794-800, (2010) Many natural products, including vitamin E, garlic, purpurogallin, flaxseed and its components [secoisolariciresinol diglucoside (SDG) and flax lignan complex (FLC)] and resveratrol have been reported to suppress hypercholesterolemic atherosclerosis. It is kn... |
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Concentration kinetics of secoisolariciresinol diglucoside and its biosynthetic precursor coniferin in developing flaxseed.
Phytochem. Anal. 24(1) , 41-6, (2013) In the plant kingdom, flaxseed (Linum usitatissimum L.) is the richest source of secoisolariciresinol diglucoside (SDG), which is of great interest because of its potential health benefits for human beings. The information about the kinetics of SDG formation ... |
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Novel synthetic (S,S) and (R,R)-secoisolariciresinol diglucosides (SDGs) protect naked plasmid and genomic DNA From gamma radiation damage.
Radiat. Res. 182(1) , 102-10, (2014) Secoisolariciresinol diglucoside (SDG) is the major lignan in wholegrain flaxseed. However, extraction methods are complex and are associated with low yield and high costs. Using a novel synthetic pathway, our group succeeded in chemically synthesizing SDG (S... |