2-硫代巴比妥酸
2-硫代巴比妥酸结构式
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常用名 | 2-硫代巴比妥酸 | 英文名 | 4,6-Dihydroxy-2-mercaptopyrimidine |
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| CAS号 | 504-17-6 | 分子量 | 144.152 | |
| 密度 | 1.6±0.1 g/cm3 | 沸点 | 463.4ºC at 760 mmHg | |
| 分子式 | C4H4N2O2S | 熔点 | 245 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 234ºC |
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Rehmannia glutinosa (Gaertn.) DC. polysaccharide ameliorates hyperglycemia, hyperlipemia and vascular inflammation in streptozotocin-induced diabetic mice.
J. Ethnopharmacol. 164 , 229-38, (2015) Rehmannia glutinosa (Gaertn.) DC. (RG) has been widely used as traditional Chinese herbal medicine for treatment of diabetes and its complications. The polysaccharide fraction of RG has been proposed to possess hypoglycemic effect by intraperitoneal administr... |
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Tibolone prevents oxidation and ameliorates cholinergic deficit induced by ozone exposure in the male rat hippocampus.
Neurochem. Res. 39(9) , 1776-86, (2014) Oxidative stress is related to the development of central nervous system diseases involving memory processes. Cholinergic system and memory processes are disrupted by ozone exposure. In rats, ozone induces motor disturbances and memory deficits as well as bio... |
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Vegetables' juice influences polyol pathway by multiple mechanisms in favour of reducing development of oxidative stress and resultant diabetic complications.
Pharmacogn. Mag. 10(Suppl 2) , S383-91, (2014) Hyperglycemia induced generation of free radicals and consequent development of oxidative stress by polyol pathway is one of the crucial mechanisms stirring up development of diabetic complications. We evaluated influence of ten vegetables' juice on polyol pa... |
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The N terminus of type III secretion needle protein YscF from Yersinia pestis functions to modulate innate immune responses.
Infect. Immun. 83(4) , 1507-22, (2015) The type III secretion system is employed by many pathogens, including the genera Yersinia, Shigella, Pseudomonas, and Salmonella, to deliver effector proteins into eukaryotic cells. The injectisome needle is formed by the polymerization of a single protein, ... |
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Differential protective effects of extra virgin olive oil and corn oil in liver injury: a proteomic study.
Food Chem. Toxicol. 74 , 131-8, (2014) Extra virgin olive oil (EVOO) presents benefits against chronic liver injury induced by hepatotoxins such as carbon tetrachloride (CCl4); however, the protective mechanisms remain unclear. In the present study, a two-dimensional gel based proteomic approach w... |
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Fungal metabolite nigerloxin ameliorates diabetic nephropathy and gentamicin-induced renal oxidative stress in experimental rats.
Naunyn Schmiedebergs Arch. Pharmacol. 387(9) , 849-59, (2014) Elevated polyol pathway enzyme activities and oxidative stress play an important role in the development and progression of diabetic nephropathy. Here, we investigated the beneficial influence of nigerloxin, a fungal metabolite and a potent aldose reductase i... |
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Cranberry flavonoids prevent toxic rat liver mitochondrial damage in vivo and scavenge free radicals in vitro.
Cell Biochem. Funct. 33 , 202-10, (2015) The present study was undertaken for further elucidation of the mechanisms of flavonoid biological activity, focusing on the antioxidative and protective effects of cranberry flavonoids in free radical-generating systems and those on mitochondrial ultrastruct... |
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Cardiovascular disease-related parameters and oxidative stress in SHROB rats, a model for metabolic syndrome.
PLoS ONE 9(8) , e104637, (2014) SHROB rats have been suggested as a model for metabolic syndrome (MetS) as a situation prior to the onset of CVD or type-2 diabetes, but information on descriptive biochemical parameters for this model is limited. Here, we extensively evaluate parameters rela... |
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The traditional drug Gongjin-Dan ameliorates chronic fatigue in a forced-stress mouse exercise model.
J. Ethnopharmacol. 168 , 268-78, (2015) Gongjin-Dan is a representative traditional Oriental medicine herbal drug that has been used to treat chronic fatigue symptoms for several hundred years. We evaluated the anti-fatigue effects of Gongjin-Dan and the underlying mechanisms in a chronic forced ex... |
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Spironolactone and dimethylsulfoxide effect on glucose metabolism and oxidative stress markers in polycystic ovarian syndrome rat model.
Exp. Clin. Endocrinol. Diabetes 122(3) , 154-62, (2014) Because polycystic ovarian syndrome (PCOS) is a risk factor for type 2 diabetes, the affected women can present frequently prediabetic states such as impaired fasting glycaemia and/or impaired glucose tolerance. The purpose of our study is to explore the effe... |