三赖氨酸
三赖氨酸结构式
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常用名 | 三赖氨酸 | 英文名 | H-Lys-Lys-Lys-OH acetate salt |
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| CAS号 | 13184-14-0 | 分子量 | 402.53200 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C18H38N6O4 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Characterization of lysine-guanine cross-links upon one-electron oxidation of a guanine-containing oligonucleotide in the presence of a trilysine peptide.
J. Am. Chem. Soc. 128 , 5703-5710, (2006) Formation of DNA-protein cross-links involving the initial formation of a guanine radical cation was investigated. For this purpose, riboflavin-mediated photosensitization of a TGT oligonucleotide in aerated aqueous solution in the presence of the KKK tripept... |
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Double-shell gold nanoparticle-based DNA-carriers with poly-L-lysine binding surface.
Biomaterials 32 , 3312-3321, (2011) In view of the prospective applications of polyamine coatings in functional gold nanoparticles for use as carriers in gene delivery systems, in tissue repair and as bactericidal and virucidal non-toxic vehicle, we have investigated the interactions of poly-l-... |
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Mechanistic differences in DNA nanoparticle formation in the presence of oligolysines and poly-L-lysine.
Biomacromolecules 8 , 477-484, (2007) We studied the effectiveness of trilysine (Lys3), tetralysine (Lys4), pentalysine (Lys5), and poly-l-lysine (PLL) (MW 50000) on lambda-DNA nanoparticle formation and characterized the size, shape, and stability of nanoparticles. Light scattering experiments s... |
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Effect of association with sulfate on the electrophoretic mobility of polyarginine and polylysine.
J. Phys. Chem. B 114 , 11934-11941, (2010) Domains rich in cationic amino acids are ubiquitous in peptides with the ability to cross cell membranes, which is likely related to the binding of such polypeptides to anionic groups on the membrane surface. To shed more light on these interactions, we inves... |
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Dispersions based on noble metal nanoparticles-DNA conjugates.
Adv. Colloid Interface Sci. 163 , 123-143, (2011) Many biomolecules have specific binding properties in the nanostructure formation; they are attractive materials for nanotechnology. One such promising construction material for growing a well-defined nanostructure is deoxyribonucleic acid, due to its π-elect... |
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Structural and functional consequences of poly(ethylene glycol) inclusion on DNA condensation for gene delivery.
Microsc. Res. Tech. 73 , 866-877, (2010) Polycationic polymers have been used to condense therapeutic DNA into submicron particles, offering protection from shear-induced or enzymatic degradation. However, the spontaneous nature of this self-assembly process gives rise to the formation of multimolec... |
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Poly(L-lysine)-induced aggregation of single-strand oligo-DNA-modified gold nanoparticles.
Chemistry 15 , 13135-13140, (2009) Single-strand oligo-DNA-modified Au nanoparticles (AuNPs) undergo aggregation in the presence of poly(L-lysine) (PLL), which is attributed to the interactions between the oligo-DNA and PLL. These interactions between the oligo-DNA and PLL were identified to b... |
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A tetra(L-lysine)-grafted poly(organophosphazene) for gene delivery.
Bioorg. Med. Chem. Lett. 17 , 2975-2978, (2007) In order to develop a new gene delivery vector, a novel cationic poly(organophosphazene) was synthesized by stepwise nucleophilic substitutions of poly(dichlorophosphazene) with a hydrophilic methoxy-poly(ethylene glycol) (MPEG) as a shielding group and a bra... |
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Syndecan-1 and FGF-2, but not FGF receptor-1, share a common transport route and co-localize with heparanase in the nuclei of mesenchymal tumor cells.
PLoS ONE 4 , e7346, (2009) Syndecan-1 forms complexes with growth factors and their cognate receptors in the cell membrane. We have previously reported a tubulin-mediated translocation of syndecan-1 to the nucleus. The transport route and functional significance of nuclear syndecan-1 i... |
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Increased infarct wall thickness by a bio-inert material is insufficient to prevent negative left ventricular remodeling after myocardial infarction.
PLoS ONE 6 , e21571, (2011) Several injectable materials have been shown to preserve or improve cardiac function as well as prevent or slow left ventricular (LV) remodeling post-myocardial infarction (MI). However, it is unclear as to whether it is the structural support or the bioactiv... |