N-乙酰-L-谷氨酸
N-乙酰-L-谷氨酸结构式
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常用名 | N-乙酰-L-谷氨酸 | 英文名 | N-Acetyl-L-glutamic acid |
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| CAS号 | 1188-37-0 | 分子量 | 189.166 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 495.9±35.0 °C at 760 mmHg | |
| 分子式 | C7H11NO5 | 熔点 | 194-196 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 253.7±25.9 °C |
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Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.
Nature 457(7231) , 910-4, (2009) Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the identification of critical biomarkers for cancer invasion an... |
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Highly sensitive GC/MS/MS method for quantitation of amino and nonamino organic acids.
Anal. Chem. 83(7) , 2705-11, (2011) Metabolite profiling methods are important tools for measurement of metabolite pools in biological systems. While most metabolite profiling methods report relative intensities or depend on a few internal standards representing all metabolites, the ultimate re... |
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Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism.
Clin. Biochem. 38(11) , 997-1008, (2005) To set up a novel simple, sensitive, and reliable ion-pairing HPLC method for the synchronous separation of several purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis and screening of inborn errors of metabolism ... |
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Effects of background anionic compounds on the activity of the hammerhead ribozyme in Mg(2+)-unsaturated solutions.
J. Biol. Inorg. Chem. 20 , 1049-58, (2015) Cellular ribozymes exhibit catalytic activity in media containing large numbers of anionic compounds and macromolecules. In this study, the RNA cleavage activity of the hammerhead ribozyme induced by Mg(2+) was investigated using the solutions containing back... |
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Liquid chromatographic-mass spectrometric analysis of N-acetylamino acids in human urine.
J. Chromatogr. B, Biomed. Appl. 657(1) , 15-21, (1994) Liquid chromatography-atmospheric pressure chemical-ionization mass spectrometry (LC-APCI-MS) was used for the analysis of N-acetylamino acids that could not be determined with an amino acid analyzer. LC-APCI-MS could directly detect the protonated molecular ... |
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Selenium and selenomethionine levels in prostate cancer patients.
Cancer Detect. Prev. 28(1) , 8-16, (2004) Selenium (Se) and selenomethionine (Se-Met) have been identified as potential chemopreventive agents of prostate cancer. Using an assay for the speciation (separation and identification) and quantification of selenoamino acids, Se-Met was profiled in serum an... |
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Urinary unconjugated 5 alpha-androstane-3 alpha, 17 beta-diol in patients with prostatic tumours.
Urol. Res. 10(2) , 81-4, (1982) A sensitive and reliable radioimmunoassay (RIA) for urinary unconjugated 5 alpha-androstane-3 alpha, 17 beta-diol is described. The mean overall recovery of unconjugated 5 alpha-androstane-3 alpha, 17 beta-diol was found to be 57.4%. The sensitivity of the as... |
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Plasma carotenoids, retinol, and tocopherols and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition study.
Am. J. Clin. Nutr. 86(3) , 672-81, (2007) Previous studies suggest that high plasma concentrations of carotenoids, retinol, or tocopherols may reduce the risk of prostate cancer.We aimed to examine the associations between plasma concentrations of 7 carotenoids, retinol, alpha-tocopherol, and gamma-t... |
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Immunochemical analysis of carbamyl phosphate synthetase I and ornithine transcarbamylase deficient livers: elevated N-acetylglutamate level in a liver lacking carbamyl phosphate synthetase protein.
Clin. Invest. Med. 13(4) , 183-8, (1990) Liver tissue from 3 patients with carbamyl phosphate synthetase I deficiency and 11 patients with ornithine transcarbamylase deficiency was analyzed by Western blots for the presence of carbamyl phosphate synthetase I and ornithine transcarbamylase cross-reac... |
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Normal N-acetylglutamate concentration measured in liver from a new patient with N-acetylglutamate synthetase deficiency: physiologic and biochemical implications.
Biochem. Med. Metab. Biol. 47(1) , 38-46, (1992) N-Acetyl-L-glutamate synthetase (NAG synthetase) is a mitochondrial matrix enzyme which catalyzes the synthesis of N-acetyl-Lglutamate (NAG), a physiologic activator of the urea cycle enzyme carbamylphosphate synthetase I. Deficiency of NAG synthetase in huma... |