奥美沙坦酯
奥美沙坦酯结构式
|
常用名 | 奥美沙坦酯 | 英文名 | Olmesartan medoxomil |
|---|---|---|---|---|
| CAS号 | 144689-63-4 | 分子量 | 558.585 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 804.2±75.0 °C at 760 mmHg | |
| 分子式 | C29H30N6O6 | 熔点 | 180°C | |
| MSDS | 中文版 美版 | 闪点 | 440.2±37.1 °C |
|
Olmesartan medoxomil reverses glomerulosclerosis in renal tissue induced by myocardial infarction without changes in renal function.
Exp. Ther. Med. 8(1) , 105-109, (2014) The aim of the present study was to investigate the effect of olmesartan medoxomil (OLM) on renal injury in mice with myocardial infarction (MI). A total of 33 male C57/BL/6 mice were divided into a sham surgery group (SHAM group), MI group (MI group) and OLM... |
|
|
Linear mixed-effects model of QTc prolongation for olmesartan medoxomil.
J. Clin. Pharmacol. , doi:10.1002/jcph.572, (2015)
|
|
|
The new oral angiotensin II antagonist olmesartan medoxomil: a concise overview.
J. Hum. Hypertens. 16 Suppl 2 , S13-6, (2002) The new orally active angiotensin II (A II) type-1 receptor antagonist olmesartan medoxomil is a prodrug, which is rapidly converted in vivo to the active metabolite, olmesartan. The pharmacology, antihypertensive efficacy and safety of olmesartan medoxomil a... |