N-α-苯甲酰-DL-精氨酰-4-硝基苯胺盐酸盐
N-α-苯甲酰-DL-精氨酰-4-硝基苯胺盐酸盐结构式
|
常用名 | N-α-苯甲酰-DL-精氨酰-4-硝基苯胺盐酸盐 | 英文名 | N-Benzoyl-DL-arginine-4-nitroanilide hydrochloride |
|---|---|---|---|---|
| CAS号 | 911-77-3 | 分子量 | 434.88 | |
| 密度 | 1.37g/cm3 | 沸点 | N/A | |
| 分子式 | C19H23ClN6O4 | 熔点 | 268-272 ºC | |
| MSDS | 美版 | 闪点 | N/A |
|
Peptide splicing in a double-sequence analogue of trypsin inhibitor SFTI-1 substituted in the P₁ positions by peptoid monomers.
Biopolymers 104 , 206-12, (2015) Recently, we described a process of trypsin-assisted peptide splicing of analogs of trypsin inhibitor SFTI-1, that seems to be very similar to proteasome-catalyzed peptide splicing. Here, we show, for the first time, that a peptide-peptoid hybrid (peptomer) c... |
|
|
A salt-bridge stabilized C-terminal hook is critical for the dimerization of a Bowman Birk inhibitor.
Arch. Biochem. Biophys. 566 , 15-25, (2015) Legume Bowman-Birk inhibitors (BBIs) that inhibit mammalian proteases exist as dimers in solution. The structural basis governing dimerization of HGI-III (horsegram seed BBI) was investigated. An intra-monomer salt bridge (D76-K71) stabilizes an atypical hook... |
|
|
Proteolysis is a confounding factor in the interpretation of faecal calprotectin.
Clin. Chem. Lab Med. 53(1) , 65-71, (2014) Calprotectin is a 36 kDa calcium and zinc binding protein. An increased level of calprotectin points towards inflammatory bowel disease. However, the biomarker calprotectin shows 14 potential cleavages sites for trypsin. Next to trypsin, also the presence of ... |
|
|
Preventive effect of phytic acid on lysosomal hydrolases in normal and isoproterenol-induced myocardial infarction in Wistar rats.
Toxicol. Mech. Methods 25(2) , 150-4, (2015) This study was aimed to evaluate the preventive role of phytic acid on lysosomal enzymes in isoproterenol (ISO)-induced myocardial infarction (MI) in male Wistar rats. Rats subcutaneously injected with ISO (85 mg/kg) at an interval of 24 h for two days showed... |
|
|
A chymotrypsin from the Digestive Tract of California Spiny Lobster, Panulirus interruptus: Purification and Biochemical Characterization.
Mar. Biotechnol. 17 , 416-27, (2015) A chymotrypsin was purified from the gastric juice of California spiny lobster (Panulirus interrutpus), using preparative electrophoresis and affinity chromatography on agarose-p-aminobenzamidine. The molecular mass was estimated by polyacrylamide gel electro... |
|
|
The anthelmintic efficacy of natural plant cysteine proteinases against Hymenolepis microstoma in vivo.
J. Helminthol. 89 , 601-11, (2015) Little is known about the efficacy of cysteine proteinases (CP) as anthelmintics for cestode infections in vivo. Hymenolepis microstoma is a natural parasite of house mice, and provides a convenient model system for the assessment of novel drugs for anthelmin... |
|
|
Evaluation of Pseudotrypsin Cleavage Specificity Towards Proteins by MALDI-TOF Mass Spectrometry.
Protein Pept. Lett. 22 , 1123-32, (2015) Trypsin is a protease, which is commonly used for the digestion of protein samples in proteomic experiments. The process of trypsin autolysis is known to produce autolytic peptides as well as active enzyme forms with one or more intra-chain splits. In consequ... |
|
|
The protective role of the Bowman-Birk protease inhibitor in soybean lunasin digestion: the effect of released peptides on colon cancer growth.
Food Funct. 6 , 2626-35, (2015) Lunasin is a naturally-occurring peptide demonstrating chemopreventive, antioxidant and anti-inflammatory properties. To exhibit these activities, orally ingested lunasin needs to survive proteolytic attack of digestive enzymes to reach target tissues in acti... |
|
|
Immobilization of trypsin in organic and aqueous media for enzymatic peptide synthesis and hydrolysis reactions.
BMC Biotechnol. 15 , 77, (2015) Immobilization of enzymes onto different carriers increases enzyme's stability and reusability within biotechnological and pharmaceutical applications. However, some immobilization techniques are associated with loss of enzymatic specificity and/or activity. ... |
|
|
Faecal leukocyte esterase activity is an alternative biomarker in inflammatory bowel disease.
Clin. Chem. Lab Med. 53 , 2003-8, (2015) Leukocyte cytosolic proteins (e.g., calprotectin) are emerging biomarkers for inflammatory bowel disease. Leukocyte aryl esterase activity has been commonly used for sensitive detection of leukocytes in human body fluids such as urine. Urine test strip result... |