3,3′,5,5′-四甲基联苯胺(TMB)
3,3′,5,5′-四甲基联苯胺(TMB)结构式
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常用名 | 3,3′,5,5′-四甲基联苯胺(TMB) | 英文名 | Tetramethylbenzidine |
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| CAS号 | 54827-17-7 | 分子量 | 240.343 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 368.6±37.0 °C at 760 mmHg | |
| 分子式 | C16H20N2 | 熔点 | 168-171 °C(lit.) | |
| MSDS | 美版 | 闪点 | 210.8±26.0 °C |
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Evaluation of the immune response and protective efficacy of Schistosoma mansoni Cathepsin B in mice using CpG dinucleotides as adjuvant.
Vaccine 33(2) , 346-53, (2014) Schistosomiasis is the most important human helminth infection due to its impact on public health. Worldwide, schistosomiasis is estimated to infect at least 200 million individuals while 700 million are at risk. The clinical manifestations are chronic and si... |
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Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease.
Brain Behav. 3(2) , 75-88, (2013) Cerebral dopamine neurotrophic factor (CDNF) protein has been shown to protect the nigrostriatal dopaminergic pathway when given as intrastriatal infusions in rat and mouse models of Parkinson's disease (PD). In this study, we assessed the neuroprotective eff... |
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MHC class II presentation is controlled by the lysosomal small GTPase, Arl8b.
J. Immunol. 194(5) , 2079-88, (2015) Dendritic cells (DCs) are specialized APCs with the ability to prime naive T cells. DCs first sample Ags from the environment and then orchestrate their processing and loading onto MHC class II (MHC II) Ag-presenting molecules in lysosomes. Once MHC II molecu... |
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Thermostable ricin vaccine protects rhesus macaques against aerosolized ricin: Epitope-specific neutralizing antibodies correlate with protection.
Proc. Natl. Acad. Sci. U. S. A. 112(12) , 3782-7, (2015) Ricin toxin (RT) is the second most lethal toxin known; it has been designated by the CDC as a select agent. RT is made by the castor bean plant; an estimated 50,000 tons of RT are produced annually as a by-product of castor oil. RT has two subunits, a riboto... |
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Investigation of the interactions between the EphB2 receptor and SNEW peptide variants.
Growth Factors 32(6) , 236-46, (2014) EphB2 interacts with cell surface-bound ephrin ligands to relay bidirectional signals. Overexpression of the EphB2 receptor protein has been linked to different types of cancer. The SNEW (SNEWIQPRLPQH) peptide binds with high selectivity and moderate affinity... |
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Development of antibodies for determination of alkylresorcinol metabolites in human urine and elucidation of ELISA cross-reactivity.
J. Immunol. Methods 413 , 12-24, (2014) Alkylresorcinols (ARs) are amphiphilic phenolic lipids and their two main metabolites, 3-(3,5-dihydroxyphenyl)-propanoic acid (DHPPA) and 3,5-dihydroxybenzoic acid (DHBA), can be used as biomarkers of whole grain wheat and rye intake. The aim of this study wa... |
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Development and in-house validation of an allergen-specific ELISA for quantification of Bet v 4 in diagnostic and therapeutic birch allergen products.
Anal. Bioanal. Chem 407(6) , 1673-83, (2015) Birch (Betula) pollen is a major cause of allergy in northern and central Europe. The allergenic potency of products for diagnosis and therapy of birch pollen allergy is adjusted nearly exclusively to the major birch pollen allergen Bet v 1. Although every fi... |
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Isolation and transplantation of sturgeon early-stage germ cells.
Theriogenology 83(6) , 1085-92, (2015) We report, for the first time, a series of baseline techniques comprising isolation and transplantation of female and male early-stage germ cells in sturgeon to generate a germline chimera as a potential tool for surrogate reproduction and gene banking. Cells... |
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Proteomics-based identification of immunodominant proteins of Brucellae using sera from infected hosts points towards enhanced pathogen survival during the infection.
Biochem. Biophys. Res. Commun. 456(1) , 202-6, (2014) Brucella (B.) species lack classical virulence factors, but escape effectively the immune response of the host. The species Brucella abortus and Brucella melitensis infect predominantly cattle and small ruminants such as sheep or goats, respectively, but acco... |
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Diminished humoral responses against and reduced gene expression levels of human endogenous retrovirus-K (HERV-K) in psoriasis.
J. Transl. Med. 12 , 256, (2014) Psoriasis is a multifactorial, chronic disease of skin affecting 2-3% of the world's population. Genetic studies of psoriasis have identified a number of susceptibility genes that are involved in anti-viral immunity. Furthermore, physiological studies have al... |