2-(3-氯丙基)-1,3-二噁戊环
2-(3-氯丙基)-1,3-二噁戊环结构式
|
常用名 | 2-(3-氯丙基)-1,3-二噁戊环 | 英文名 | 2-(3-Chloropropyl)-1,3-dioxolane |
|---|---|---|---|---|
| CAS号 | 16686-11-6 | 分子量 | 150.603 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 199.5±15.0 °C at 760 mmHg | |
| 分子式 | C6H11ClO2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 75.3±15.6 °C |
|
High yield conversion of doxorubicin to 2-pyrrolinodoxorubicin, an analog 500-1000 times more potent: structure-activity relationship of daunosamine-modified derivatives of doxorubicin.
Proc. Natl. Acad. Sci. U. S. A. 93(6) , 2464-2469, (1996) A convenient, high yield conversion of doxorubicin to 3'-deamino-3'-(2''-pyrroline-1''-yl)doxorubicin is described. This daunosamine-modified analog of doxorubicin is 500-1000 times more active in vitro than doxorubicin. The conversion is effected by using a ... |
|
|
P.A. Aristoff
J. Org. Chem. 50 , 1765, (1985)
|
|
|
S.A. Bal et al.
J. Org. Chem. 47 , 5045, (1982)
|
|
|
C.P. Forbes et al.
J. Chem. Soc. Perkin Trans. I , 2353, (1977)
|
|
|
R.E. Abbott, T.A. Spencer
J. Org. Chem. 45 , 5398, (1980)
|
|
|
Two-directional synthesis. Part 1: A short formal synthesis of (±)-histrionicotoxin and (±)-histrionicotoxin 235A. Stockman RA.
Tetrahedron Lett. 41(47) , 9163-65, (2000)
|