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三磷酸尿苷三钠

三磷酸尿苷三钠结构式
三磷酸尿苷三钠结构式
品牌特惠专场
常用名 三磷酸尿苷三钠 英文名 URIDINE 5'-TRIPHOSPHATE TRISODIUM SALT
CAS号 116295-90-0 分子量 586.11700
密度 N/A 沸点 N/A
分子式 C9H16N2Na3O17P3 熔点 >140ºC (dec.)(lit.)
MSDS 美版 闪点 >230 °F

Cell-free expression and in meso crystallisation of an integral membrane kinase for structure determination.

Cell. Mol. Life Sci. 71(24) , 4895-910, (2014)

Membrane proteins are key elements in cell physiology and drug targeting, but getting a high-resolution structure by crystallographic means is still enormously challenging. Novel strategies are in big demand to facilitate the structure determination process t...

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

Nat. Commun. 6 , 6281, (2015)

In asthma, airflow obstruction is thought to result primarily from inflammation-triggered airway smooth muscle (ASM) contraction. However, anti-inflammatory and smooth muscle-relaxing treatments are often temporary or ineffective. Overproduction of the mucin ...

RIC8 is a guanine-nucleotide exchange factor for Galpha subunits that regulates growth and development in Neurospora crassa.

Genetics 189 , 165-176, (2011)

Heterotrimeric (αβγ) G proteins are crucial components of eukaryotic signal transduction pathways. G-protein-coupled receptors (GPCRs) act as guanine nucleotide exchange factors (GEFs) for Gα subunits. Recently, facilitated GDP/GTP exchange by non-GPCR GEFs, ...

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

J. Cell Biol. 191 , 367-381, (2010)

A key requirement for Rab function in membrane trafficking is site-specific activation by GDP-GTP exchange factors (GEFs), but the majority of the 63 human Rabs have no known GEF. We have performed a systematic characterization of the 17 human DENN domain pro...

APC(cdh1) mediates degradation of the oncogenic Rho-GEF Ect2 after mitosis.

PLoS ONE 6 , e23676, (2011)

Besides regulation of actin cytoskeleton-dependent functions, Rho GTPase pathways are essential to cell cycle progression and cell division. Rho, Rac and Cdc42 regulate G1 to S phase progression and are involved in cytokinesis. RhoA GDP/GTP cycling is require...

Ubiquitination in Rho signaling.

Curr. Top. Med. Chem 11(23) , 2879-2887, (2011)

The Rho family small GTPases of the Ras superfamily play key roles in regulating diverse signaling pathways that control a myriad of fundamental cellular processes such as cytoskeletal dynamics, cell cycle progression, gene expression, cell polarity, migratio...