神经节肽(抗原)
神经节肽(抗原)结构式
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常用名 | 神经节肽(抗原) | 英文名 | Galanin (porcine) trifluoroacetate salt |
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| CAS号 | 88813-36-9 | 分子量 | 3210.52000 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C146H213N43O40 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Neuroanatomy of the kisspeptin signaling system in mammals: comparative and developmental aspects.
Adv. Exp. Med. Biol. 784 , 27-62, (2013) Our understanding of kisspeptin and its actions depends, in part, on a detailed knowledge of the neuroanatomy of the kisspeptin signaling system in the brain. In this chapter, we will review our current knowledge of the distribution of kisspeptin cells, fiber... |
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Concurrent modulation of extracellular levels of noradrenaline and cAMP during stress and by anxiogenic- or anxiolytic-like neuropeptides in the prefrontal cortex of awake rats.
Neurochem. Int. 62(3) , 314-23, (2013) The purpose of this study was to examine the effects of stress and the role of locally infused anxiogenic-like neuropeptides galanin, CCK-8, vasopressin, substance P and neurokinin A, and anxiolytic-like peptides NPY, nociceptin/orphanin FQ, somatostatin and ... |
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Inhibitory control of the cough reflex by galanin receptors in the caudal nucleus tractus solitarii of the rabbit.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(11) , R1358-67, (2014) The caudal nucleus tractus solitarii (NTS) is the main central station of cough-related afferents and a strategic site for the modulation of the cough reflex. The similarities between the characteristics of central processing of nociceptive and cough-related ... |
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Coevolution of the spexin/galanin/kisspeptin family: Spexin activates galanin receptor type II and III.
Endocrinology 155(5) , 1864-73, (2014) The novel neuropeptide spexin (SPX) was discovered using bioinformatics. The function of this peptide is currently under investigation. Here, we identified SPX along with a second SPX gene (SPX2) in vertebrate genomes. Syntenic analysis and relocating SPXs an... |
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Combined galanin with insulin improves insulin sensitivity of diabetic rat muscles.
J. Endocrinol. 221(1) , 157-65, (2014) Although administration of galanin or insulin alone may enhance insulin sensitivity and glucose transporter 4 (GLUT4) trafficking, their cooperative effect on insulin sensitivity is still unclear. In the present study, we evaluated the cooperative effect of b... |
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Leptin receptor neurons in the mouse hypothalamus are colocalized with the neuropeptide galanin and mediate anorexigenic leptin action.
Am. J. Physiol. Endocrinol. Metab. 304(9) , E999-1011, (2013) Leptin acts centrally via leptin receptor (LepRb)-expressing neurons to regulate food intake, energy expenditure, and other physiological functions. LepRb neurons are found throughout the brain, and several distinct populations contribute to energy homeostasi... |
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Galanin, through GalR1 but not GalR2 receptors, decreases motivation at times of high appetitive behavior.
Behav. Brain Res. 239 , 90-3, (2013) Galanin is a 29/30-amino acid long neuropeptide that has been implicated in many physiological and behavioral functions. Previous research has shown that i.c.v. administration of galanin strongly stimulates food intake in sated rats when food is freely availa... |
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Identification of galanin and its receptor GalR1 as novel determinants of resistance to chemotherapy and potential biomarkers in colorectal cancer.
Clin. Cancer Res. 18(19) , 5412-26, (2012) A major factor limiting the effective clinical management of colorectal cancer (CRC) is resistance to chemotherapy. Therefore, the identification of novel, therapeutically targetable mediators of resistance is vital.We used a CRC disease-focused microarray pl... |
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Galanin is a modulator of eccrine sweat gland secretion.
Exp. Dermatol. 22(2) , 141-3, (2013) The neuropeptide galanin has been ascribed different roles in modulating physiological functions in the skin. The present study examined the function of galanin in eccrine sweat gland physiology. We demonstrated secretion of galanin by sweat glands in vivo by... |
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Cyclic analogs of galanin and neuropeptide Y by hydrocarbon stapling.
Bioorg. Med. Chem. 21(1) , 303-10, (2013) Hydrocarbon stapling is an effective strategy to stabilize the helical conformation of bioactive peptides. Here we describe application of stapling to anticonvulsant neuropeptides, galanin (GAL) and neuropeptide Y (NPY), that are implicated in modulating seiz... |