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(±)-1-[2,3-(二氢-7-甲基1H-茚-4-基)氧]-3-[(1-甲基乙基)氨基]-2-丁醇盐酸盐

(±)-1-[2,3-(二氢-7-甲基1H-茚-4-基)氧]-3-[(1-甲基乙基)氨基]-2-丁醇盐酸盐结构式
(±)-1-[2,3-(二氢-7-甲基1H-茚-4-基)氧]-3-[(1-甲基乙基)氨基]-2-丁醇盐酸盐结构式
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常用名 (±)-1-[2,3-(二氢-7-甲基1H-茚-4-基)氧]-3-[(1-甲基乙基)氨基]-2-丁醇盐酸盐 英文名 ici-118,551
CAS号 72795-19-8 分子量 313.86300
密度 N/A 沸点 439.3ºC at 760 mmHg
分子式 C17H28ClNO2 熔点 N/A
MSDS 中文版 美版 闪点 219.5ºC

Beta 1- and beta 2-adrenergic receptor-mediated adenylate cyclase stimulation in nonfailing and failing human ventricular myocardium.

Mol. Pharmacol. 35 , 295-303, (1989)

Prenalterol (beta 1-agonist), denopamine (beta 1-agonist), and zinterol (beta 2-agonist) were partial agonists of adenylate cyclase (AC) stimulation in human ventricular myocardium obtained from nonfailing chambers whose beta 1/beta 2 receptor subtype ratio w...

Species differences in the localization and number of CNS beta adrenergic receptors: rat versus guinea pig.

J. Pharmacol. Exp. Ther. 249 , 911-920, (1989)

The localization and number of beta adrenergic receptors were directly compared in the brains of rats and guinea pigs. The time course of association and saturability of [125I]cyanopindolol (CYP) binding to slide-mounted tissue sections was similar in rats (K...

The pharmacology of a beta 2-selective adrenoceptor antagonist (ICI 118,551).

J. Cardiovasc. Pharmacol. 5 , 430, (1983)

While specific antagonists of the beta 1-adrenoceptor, such as atenolol and betaxolol, are widely available, a potent specific antagonist selective for the beta 2-adrenoceptor has yet to be described. Previously described beta 2-selective antagonists such as ...

Implications of a vasodilatory human monoclonal autoantibody in postural hypotension.

J. Biol. Chem. 288(42) , 30734-41, (2013)

Functional autoantibodies to the autonomic receptors are increasingly recognized in the pathophysiology of cardiovascular diseases. To date, no human activating monoclonal autoantibodies to these receptors have been available. In this study, we describe for t...