甘氨酰胺盐酸盐
甘氨酰胺盐酸盐结构式
|
常用名 | 甘氨酰胺盐酸盐 | 英文名 | H-Gly-NH2.HCl |
|---|---|---|---|---|
| CAS号 | 1668-10-6 | 分子量 | 110.54 | |
| 密度 | 1.122g/cm3 | 沸点 | 281.3ºC at 760mmHg | |
| 分子式 | C2H7ClN2O | 熔点 | 204 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | N/A |
|
Preparation of guanine and diaminopurine from biuret. Part III.
Chem. Biodivers. 4(4) , 818-22, (2007) Because of their potential prebiotic origin and relative chemical stability, urea, biuret, formic acid, and glycine amide might have played a role in the assembly process of purine bases. In this paper, we describe a short reaction path to purine nucleobases ... |
|
|
Identification of quinoline, carboline and glycinamide compounds in cow milk using HRMS and NMR.
Food Chem. 141(3) , 1888-94, (2013) The aim of this work was to characterise new UV-absorbing compounds (UAC) in cow milk in order to gain an overview of the molecular diversity of the minor bioactive constituents, that could be used to trace animal feed or that potentially affect milk quality.... |
|
|
Synthesis of (-)-quinocarcin by directed condensation of alpha-amino aldehydes.
J. Am. Chem. Soc. 127(48) , 16796-7, (2005) An enantioselective synthesis of the natural antiproliferative agent quinocarcin was achieved by the directed condensation of optically active alpha-amino aldehyde intermediates. Condensation of the N-protected alpha-amino aldehyde 1, prepared in eight steps ... |
|
|
Clozapine and glycinamide prevent MK-801-induced deficits in the novel object recognition (NOR) test in the domestic rabbit (Oryctolagus cuniculus).
Behav. Brain Res. 271 , 203-11, (2014) Studies in humans indicate that acute administration of sub-anesthetic doses of ketamine, an NMDA receptor antagonist, provokes schizophrenic-like symptoms in healthy volunteers, and exacerbates existing symptoms in individuals with schizophrenia. These and o... |
|
|
Design and characterization of a noncompetitive antagonist of the transient receptor potential vanilloid subunit 1 channel with in vivo analgesic and anti-inflammatory activity.
J. Pain 7(10) , 735-46, (2006) Vanilloid receptor subunit 1 (TRPV1) is an integrator of physical and chemical stimuli in the peripheral nervous system. This receptor plays a key role in the pathophysiology of inflammatory pain. Thus, the identification of receptor antagonists with analgesi... |
|
|
Discovery of 3,5-bis(trifluoromethyl)benzyl L-arylglycinamide based potent CCR2 antagonists.
Bioorg. Med. Chem. Lett. 16(14) , 3735-9, (2006) Systematic modification of a screening lead yielded a class of potent glycinamide based CCR2 antagonists. The best compound (55, (2S)-N-[3,5-bis(trifluoromethyl)benzyl]-2-{[2-(1-piperidinyl)ethyl]amino}-2-(3-thienyl)acetamide) displayed good binding affinity ... |
|
|
Isolation and characterization of a small antiretroviral molecule affecting HIV-1 capsid morphology.
Retrovirology 6 , 34, (2009) Formation of an HIV-1 particle with a conical core structure is a prerequisite for the subsequent infectivity of the virus particle. We have previously described that glycineamide (G-NH2) when added to the culture medium of infected cells induces non-infectio... |
|
|
Investigation of anion retention and cation exclusion effects for several C18 stationary phases.
Anal. Chem. 79(14) , 5382-91, (2007) When mobile-phase salt content is increased, cationic analytes often show increased retention. This effect is generally attributed to chaotropic or ion pairing effects. However, a cation exclusion mechanism could explain the same effects. In this study, exper... |
|
|
Adenosine kinase inhibitors. 6. Synthesis, water solubility, and antinociceptive activity of 5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidines substituted at C4 with glycinamides and related compounds.
J. Med. Chem. 48(24) , 7808-20, (2005) 4-(Phenylamino)-5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine 1 and related compounds known as "diaryltubercidin" analogues are potent inhibitors of adenosine kinase (AK) and are orally active in animal models of pain such as the rat forma... |
|
|
One-step synthesis of hypoxanthine from glycinamide and diformylurea.
Chem. Biodivers. 1(1) , 106-11, (2004) Because of their easy availability and their relative chemical stability, urea, formic acid, and glycine might have played a role in the assembly process of nucleobases. In this paper, a short reaction path is described to prepare hypoxanthine starting from t... |