![]() DL-苏-1-苯基-2-棕榈酰氨基-3-吗啉代-1-丙醇结构式
![]() |
常用名 | DL-苏-1-苯基-2-棕榈酰氨基-3-吗啉代-1-丙醇 | 英文名 | D,L-threo-PPMP |
---|---|---|---|---|
CAS号 | 149022-18-4 | 分子量 | 511.18000 | |
密度 | 1.005g/cm3 | 沸点 | 642.8ºC at 760mmHg | |
分子式 | C29H51ClN2O3 | 熔点 | N/A | |
MSDS | 中文版 美版 | 闪点 | 342.6ºC |
Effect of chum salmon egg lectin on tight junctions in Caco-2 cell monolayers.
Molecules 20 , 8094-106, (2015) The effect of a chum salmon egg lectin (CSL3) on tight junction (TJ) of Caco-2 cell monolayers was investigated. The lectin opened TJ as indicated by the decrease of the transepithelial electrical resistance (TER) value and the increase of the permeation of l... |
|
Galactosylceramide affects tumorigenic and metastatic properties of breast cancer cells as an anti-apoptotic molecule.
PLoS ONE 8(12) , e84191, (2013) It was recently proposed that UDP-galactose:ceramide galactosyltransferase (UGT8), enzyme responsible for synthesis of galactosylceramide (GalCer), is a significant index of tumor aggressiveness and a potential marker for the prognostic evaluation of lung met... |
|
Glioma cell death induced by irradiation or alkylating agent chemotherapy is independent of the intrinsic ceramide pathway.
PLoS ONE 8(5) , e63527, (2013) Resistance to genotoxic therapy is a characteristic feature of glioma cells. Acid sphingomyelinase (ASM) hydrolyzes sphingomyelin to ceramide and glucosylceramide synthase (GCS) catalyzes ceramide metabolism. Increased ceramide levels have been suggested to e... |
|
Improved inhibitors of glucosylceramide synthase.
J. Biochem. 111 , 191, (1992) An inhibitor of glucosylceramide (GlcCer) synthase, 1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP), has been reported to deplete cells and mice of their glucosphingolipids. This inhibitor has proved useful for the elucidation of the many functions of... |
|
Cisplatin-induced expression of Gb3 enables verotoxin-1 treatment of cisplatin resistance in malignant pleural mesothelioma cells.
Br. J. Cancer 102 , 383-91, (2010) A major problem with cisplatin treatment is the development of acquired-drug resistance of the tumour cells. Verotoxin-1 (VT-1) exerts its cytotoxicity by targeting the membrane glycolipid globotriasosylceramide (Gb3), a molecule associated with drug resistan... |