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win-62577

win-62577结构式
win-62577结构式
品牌特惠专场
常用名 win-62577 英文名 win-62577
CAS号 138091-43-7 分子量 437.57600
密度 N/A 沸点 N/A
分子式 C29H31N3O 熔点 N/A
MSDS 美版 闪点 N/A

Synthesis and substance P receptor binding activity of androstano[3,2-b]pyrimido[1,2-a]benzimidazoles.

J. Med. Chem. 35 , 374, (1992)

Several heterosteroids containing a dihydroethisterone skeleton were prepared and shown to displace substance P in a receptor binding assay. Further biochemical (kinetic and Scatchard analyses) and pharmacological evaluation (substance P-induced plasma extrav...

Antagonists that demonstrate species differences in neurokinin-1 receptors.

Mol. Pharmacol. 41 , 772, (1992)

125I-Bolton-Hunter-substance P (125I-BH-SP) binding properties of three novel classes of neurokinin-1 (NK-1) receptor antagonists were investigated in tissues derived from humans, guinea pigs, and rats. 125I-BH-SP was shown to bind to a single class of bindin...