8-氨基-1,3,6-萘三磺酸二钠盐
8-氨基-1,3,6-萘三磺酸二钠盐结构式
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常用名 | 8-氨基-1,3,6-萘三磺酸二钠盐 | 英文名 | 8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt |
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| CAS号 | 5398-34-5 | 分子量 | 427.33800 | |
| 密度 | 1.974g/cm3 | 沸点 | N/A | |
| 分子式 | C10H7NNa2O9S3 | 熔点 | 138 °C (dec.)(lit.) | |
| MSDS | 美版 | 闪点 | N/A |
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Enzymatic production of specifically distributed hyaluronan oligosaccharides.
Carbohydr. Polym. 129 , 194-200, (2015) High-molecular-mass hyaluronan (HA) was controllably depolymerized in pure aqueous solution with recombinant leech hyaluronidase (HAase). The HAase concentration per unit HA and hydrolysis time played important roles in molecular mass distribution. By modulat... |
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Study of the putative fusion regions of the preS domain of hepatitis B virus.
Biochim. Biophys. Acta 1848(4) , 895-906, (2015) In a previous study, it was shown that purified preS domains of hepatitis B virus (HBV) could interact with acidic phospholipid vesicles and induce aggregation, lipid mixing and leakage of internal contents which could be indicative of their involvement in th... |
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Triatoma virus recombinant VP4 protein induces membrane permeability through dynamic pores.
J. Virol. 89(8) , 4645-54, (2015) In naked viruses, membrane breaching is a key step that must be performed for genome transfer into the target cells. Despite its importance, the mechanisms behind this process remain poorly understood. The small protein VP4, encoded by the genomes of most vir... |
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Bilayer Effects of Antimalarial Compounds.
PLoS ONE 10 , e0142401, (2015) Because of the perpetual development of resistance to current therapies for malaria, the Medicines for Malaria Venture developed the Malaria Box to facilitate the drug development process. We tested the 80 most potent compounds from the box for bilayer-mediat... |
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A cyclic GB virus C derived peptide with anti-HIV-1 activity targets the fusion peptide of HIV-1
Eur. J. Med. Chem. 86 , 589-604, (2014) The development of peptide fusion inhibitors based on short synthetic peptides represents a promising option in the fight against HIV-1 infection, especially in individuals infected with multiresistant HIV-1 strains. GBV-C has the beneficial effect of retardi... |
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The identification of a novel Sulfolobus islandicus CAMP-like peptide points to archaeal microorganisms as cell factories for the production of antimicrobial molecules.
Microb. Cell Fact. 14 , 126, (2015) Pathogenic bacteria easily develop resistance to c onventional antibiotics so that even relatively new molecules are quickly losing efficacy. This strongly encourages the quest of new antimicrobials especially for the treatment of chronic infections. Cationic... |
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Fusogenic properties of the ectodomains of hepatitis C virus envelope proteins.
FEBS J. 281(11) , 2558-69, (2014) We have used an isolated chimeric protein E1340 E2661 that includes the ectodomains of the envelope proteins of hepatitis C virus to study its interaction with model membranes. E1340 E2661 has some of the membrane destabilization properties, vesicle aggregati... |
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Structural basis for self-assembly of a cytolytic pore lined by protein and lipid.
Nat. Commun. 6 , 6337, (2015) Pore-forming toxins (PFT) are water-soluble proteins that possess the remarkable ability to self-assemble on the membrane of target cells, where they form pores causing cell damage. Here, we elucidate the mechanism of action of the haemolytic protein fragacea... |
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Investigation of Ion Channel Activities of Gramicidin A in the Presence of Ionic Liquids Using Model Cell Membranes.
Sci. Rep. 5 , 11935, (2015) Ionic liquids (ILs) are considered to be green solvents because of their non-volatility. Although ILs are relatively safe in the atmospheric environment, they may be toxic in other environments. Our previous research showed that the cytotoxicity of ILs to bio... |
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Characterization of Mycobacterium tuberculosis EsxA membrane insertion: roles of N- and C-terminal flexible arms and central helix-turn-helix motif.
J. Biol. Chem. 290(11) , 7314-22, (2015) EsxA (ESAT-6), an important virulence factor of Mycobacterium tuberculosis, plays an essential role in phagosome rupture and bacterial cytosolic translocation within host macrophages. Our previous study showed that EsxA exhibits a unique membrane-interacting ... |