4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE
![4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE结构式](https://image.chemsrc.com/caspic/024/276890-57-4.png)
4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE结构式
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常用名 | 4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE | 英文名 | 4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE |
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| CAS号 | 276890-57-4 | 分子量 | 431.01400 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C24H35ClN4O | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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CRHR1 Receptor binding and lipophilicity of pyrrolopyrimidines, potential nonpeptide corticotropin-releasing hormone type 1 receptor antagonists.
Bioorg. Med. Chem. 10 , 175-183, (2002) A series of compounds related to N-butyl-N-ethyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amine (1, antalarmin) have been prepared and evaluated for their CRHR1 binding affinity as the initial step in the development of selective ... |
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Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptors.
Science 303 , 1512-1514, (2004) The central amygdala (CeA) plays a role in the relationship among stress, corticotropin-releasing factor (CRF), and alcohol abuse. In whole-cell recordings, both CRF and ethanol enhanced gamma-aminobutyric acid-mediated (GABAergic) neurotransmission in CeA ne... |
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