甲磺酸去铁胺
甲磺酸去铁胺结构式
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常用名 | 甲磺酸去铁胺 | 英文名 | Deferoxamine (mesylate) |
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| CAS号 | 138-14-7 | 分子量 | 752.895 | |
| 密度 | N/A | 沸点 | 966.9ºC at 760 mmHg | |
| 分子式 | C26H52N6O11S | 熔点 | 148-149° | |
| MSDS | 中文版 美版 | 闪点 | 538.5ºC |
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Cryopreservation prevents iron-initiated highly unsaturated fatty acid loss during storage of human blood on chromatography paper at -20°C.
J. Nutr. 145(3) , 654-60, (2015) Fingertip prick whole blood collection on chromatography paper is amenable to high-throughput fatty acid (FA) profiling for large clinical and field studies. However, sample storage is problematic because highly unsaturated FAs (HUFAs) in erythrocytes rapidly... |
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Collagen density regulates xenobiotic and hypoxic response of mammary epithelial cells.
Environ. Toxicol. Pharmacol. 39(1) , 114-24, (2015) Breast density, where collagen I is the dominant component, is a significant breast cancer risk factor. Cell surface integrins interact with collagen, activate focal adhesion kinase (FAK), and downstream cell signals associated with xenobiotics (AhR, ARNT) an... |
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Mechanism of hydroxyl radical generation from biochar suspensions: Implications to diethyl phthalate degradation.
Bioresour. Technol. 176 , 210-7, (2014) This paper investigated hydroxyl radical (OH) generation from biochar suspensions for diethyl phthalate (DEP) degradation in the presence of oxygen. Electron paramagnetic resonance (EPR) coupled with a salicylic acid trapping method were used to detect free r... |
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Particle pollution in Rio de Janeiro, Brazil: increase and decrease of pro-inflammatory cytokines IL-6 and IL-8 in human lung cells.
Environ. Pollut. 194 , 112-20, (2014) Particle pollution from urban and industrialized regions in Rio de Janeiro (RJ), Brazil was analyzed for toxic and pro-inflammatory (cytokines: IL-6, IL-8, IL-10) responses in human bronchial epithelial cells. Trace elements contribution was studied. Airborne... |
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Retaining Oxidative Stability of Emulsified Foods by Novel Nonmigratory Polyphenol Coated Active Packaging.
J. Agric. Food Chem. 64 , 5574-82, (2016) Oxidation causes lipid rancidity, discoloration, and nutrient degradation that decrease shelf life of packaged foods. Synthetic additives are effective oxidation inhibitors, but are undesirable to consumers who prefer "clean" label products. The aim of this s... |
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Translational downregulation of HSP90 expression by iron chelators in neuroblastoma cells.
Mol. Pharmacol. 87(3) , 513-24, (2015) Iron is an essential cellular nutrient, being a critical cofactor of several proteins involved in cell growth and replication. Compared with normal cells, neoplastic cells have been shown to require a greater amount of iron, thus laying the basis for the prom... |
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Oxidative stress of alternariol in Caco-2 cells.
Toxicol. Lett. 229(3) , 458-64, (2014) Alternariol (AOH) is a mycotoxin produced by fungus Alternaria. It is found in a wide variety of fruits and cereals products. AOH is able to damage human health. The aim of this study was to evaluate the cytotoxicity of AOH in human colon adenocarcinoma (Caco... |
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Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with (89)Zr(4+): comparison with desferrioxamine-B.
Dalton Trans. 44(11) , 4884-900, (2015) Due to its long half-life (78 h) and decay properties (77% electron capture, 23% β(+), Emax = 897 keV, Eav = 397 keV, Eγ = 909 keV, Iγ = 100%) (89)Zr is an appealing radionuclide for immunoPET imaging with whole IgG antibodies. Derivatives of the siderophore ... |
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Novel DFO-SAM on mesoporous silica for iron sensing. Part I. Synthesis optimization and characterization of the material.
Analyst 139(16) , 3932-9, (2014) The synthesis and the physico-chemical characterisation of a novel solid phase, designed for iron(iii) sorption, are presented. The solid (indicated in the following as DFO-SAMMS) is made with a hydroxamate siderophore, the deferoxamine (DFO), covalently boun... |
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A dual component heme biosensor that integrates heme transport and synthesis in bacteria.
J. Microbiol. Methods 118 , 7-17, (2015) Bacterial pathogens acquire host iron to power cellular processes and replication. Heme, an iron-containing cofactor bound to hemoglobin, is scavenged by bacterial proteins to attain iron. Methods to measure intracellular heme are laborious, involve complex c... |