Palmitoylcarnitine chloride
Palmitoylcarnitine chloride结构式
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常用名 | Palmitoylcarnitine chloride | 英文名 | UNII:EIL57224QR |
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| CAS号 | 6865-14-1 | 分子量 | 436.069 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C23H46ClNO4 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Modulation by palmitoylcarnitine of protein kinase C activation.
Cancer Res. 47 , 6537-6542, (1987) Palmitoylcarnitine, a reported protein kinase C inhibitor, enhanced the phorbol ester dependency of the enzyme, augmenting protein kinase C activity in the presence of phorbol esters such as phorbol 12,13-dibutyrate while inhibiting the basal activity measure... |
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Palmitoyl-DL-carnitine has calcium-dependent effects on cultured neurones from rat dorsal root ganglia.
Br. J. Pharmacol. 107 , 1192-1197, (1992) 1. The effects of palmitoyl-DL-carnitine (0.01 to 1 mM) on whole cell voltage-activated calcium channel currents carried by calcium or barium and Ca(2+)-activated chloride currents were studied in cultured neurones from rat dorsal root ganglia. 2. Palmitoyl-D... |
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Palmitoyl-L-carnitine modifies the function of vascular endothelium.
Cardiovasc. Res. 28 , 129-134, (1994) Palmitoyl-L-carnitine, which accumulates in ischaemic myocardium, may influence the function of vascular endothelium in the ischaemic area. The aim of the study was therefore to examine the effect of palmitoyl-L-carnitine on endothelium dependent relaxations ... |
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Palmitoyl-L-carnitine modifies the myocardial levels of high-energy phosphates and free fatty acids.
Basic Res. Cardiol. 92 , 320-330, (1997) Long-chain acylcarnitines, such as palmitoyl-L-carnitine (PALCAR), are known to accumulate in the myocardium during ischemia. We examined whether exogenous PALCAR modifies the myocardial levels of high-energy phosphates (HEP) and free fatty acids (FFA) in the... |
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Effect of L-carnitine and palmitoyl-L-carnitine on erythroid colony formation in fetal mouse liver cell culture.
Am. J. Nephrol. 18 , 355-358, (1998) The administration of L-carnitine to patients undergoing hemodialysis increases hematocrit and improves the response to recombinant human erythropoietin (rhEPO). This suggests a contribution by carnitine to erythrocyte membrane function or erythropoiesis. We ... |
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Effect of membrane incorporation of 1-palmitoylcarnitine on surface charge of human erythrocytes.
J. Mol. Cell. Cardiol. 25 , 1275-1284, (1993) 1-Palmitoylcarnitine (1-PC) reduced the electrophoretic mobility of human erythrocytes bathed in low ionic strength solution. Unlike divalent cations which appear to reduce electrophoretic mobility by screening surface negative charge, cationic 1-PC does so b... |
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Palmitoyl-L-carnitine acts like ouabain on voltage, current, and contraction in guinea pig ventricular cells.
Am. J. Physiol. 268 , H1027-H1036, (1995) We previously showed that palmitoyl-L-carnitine (L-PC) inhibits the Na/K pump current (INa/K). In the present report, we test the hypothesis that L-PC, like ouabain, should increase myocyte shortening. Membrane potentials or ionic currents were recorded simul... |
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Activation and inhibition of reconstituted cardiac L-type calcium channels by palmitoyl-L-carnitine.
Biochem. Biophys. Res. Commun. 228 , 252-258, (1996) We have studied the effect of a palmitoyl-L-carnitine (L-PC) on single cardiac L-type Ca channels incorporated from porcine ventricular sarcolemma into planar lipid bilayers where we could control the concentration, intracellular and/or extracellular location... |