![]() 2'-碘马尿酸结构式
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常用名 | 2'-碘马尿酸 | 英文名 | 2'-iodohippuric acid |
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CAS号 | 147-58-0 | 分子量 | 305.06900 | |
密度 | 1.871g/cm3 | 沸点 | 480.9ºC at 760mmHg | |
分子式 | C9H8INO3 | 熔点 | 170-172 °C(lit.) | |
MSDS | 中文版 美版 | 闪点 | 244.6ºC |
Renal brush border enzyme-cleavable linkages for low renal radioactivity levels of radiolabeled antibody fragments.
Bioconjug. Chem. 24(2) , 291-9, (2013) We previously demonstrated that Fab fragments labeled with 3'-[(131)I]iodohippuryl N(ε)-maleoyl-l-lysine ([(131)I]HML) showed low renal radioactivity from early postinjection time, due to a liberation of m-[(131)I]iodohippuric acid by the action of renal brus... |
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Renal function and cardiopulmonary bypass in pediatric cardiac surgical patients.
Pediatr. Nephrol. 21(10) , 1446-51, (2006) We studied prospectively the perioperative changes of renal function in nine children undergoing cardiac surgery with cardiopulmonary bypass (CPB). Glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) were measured with inulin and (131)I-hi... |
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123I-hippuran renal scintigraphy with evaluation of single-kidney clearance for predicting renal scarring after acute urinary tract infection: comparison with (99m)Tc-DMSA scanning.
J. Nucl. Med. 44(11) , 1755-60, (2003) The value of (123)I-hippuran (OIH) renal sequential scintigraphy (RSS) in predicting the evolution of defects detected by (99m)Tc-dimercaptosuccinic acid (DMSA) scanning during a first episode of acute pyelonephritis (APN) was assessed.Fifty-eight children wi... |
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Preclinical evaluation of 99mTc(CO)3-aspartic-N-monoacetic acid, a renal radiotracer with pharmacokinetic properties comparable to 131I-o-iodohippurate.
J. Nucl. Med. 53(8) , 1277-83, (2012) In an ongoing effort to develop a renal tracer with pharmacokinetic properties comparable to p-aminohippurate and superior to those of both (99m)Tc-mercaptoacetyltriglycine and (131)I-o-iodohippurate ((131)I-OIH), we evaluated a new renal tricarbonyl radiotra... |
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Evaluation of (123)I-orthoiodohippurate single kidney clearance rate by renal sequential scintigraphy in a large cohort of likely normal subjects aged between 0 and 18 years.
Eur. J. Nucl. Med. Mol. Imaging 33(12) , 1483-90, (2006) Age-related values of (123)I-orthoiodohippurate (OIH) single kidney clearance rate (Cl) were estimated in a large cohort of likely normal children aged between 0 and 18 years.Among 4,111 children examined in the past 10 years, 917 were selected with the follo... |
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[Design of radiolabeled antibody fragments for tumor-selective radioactivity localization--brush border enzyme-sensitive bond to decrease renal accumulation of radioactivity].
Yakugaku Zasshi 123(8) , 647-52, (2003) Nonspecific renal radioactivity localization constitutes a problem in targeted imaging and therapy with radiolabeled antibody fragments. Based on the idea that the renal radioactivity levels should be reduced if radiolabeled compounds excreted in the urine ar... |
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Renogram comparison of p-[(18)F]fluorohippurate with o-[(125)I]iodohippurate and [(99m)Tc]MAG3 in normal rats.
Nucl. Med. Commun. 32(10) , 908-12, (2011) We recently identified p-[(18)F]fluorohippurate ([(18)F]PFH) as a potential positron emission tomography (PET) renal agent. The objective of this study was to compare renogram parameters of [(18)F]PFH with o-[(125)I]iodohippurate ([(125)I]OIH) as a surrogate ... |
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Excision of the dilated pelvis is not necessary in laparoscopic dismembered pyeloplasty.
Eur. J. Pediatr. Surg. 18(1) , 19-21, (2008) The surgical treatment of choice for significant hydronephrosis is dismembered pyeloplasty. While in open surgery, extensive resection of the dilated pelvis is common practice, laparoscopically usually only a sparing resection is performed. We compared the tr... |
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Evaluation of renal graft haemodynamia by 51Cr-EDTA and o-[131I]iodohippurate: its use in the early diagnosis of glomerular hyperfiltration.
Nucl. Med. Commun. 24(6) , 679-82, (2003) Chronic rejection is the most important cause of renal graft dysfunction. Non-immunological mechanisms have been suggested as a probable origin of chronic graft rejection, provoking a decrease in renal mass function, followed by glomerular hyperfiltration in ... |
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Technetium-99m DTPA dimethyl ester: a renal function imaging agent. Comparative studies in animals with technetium-99m mercaptoacetyl triglycine and 131I-ortho-iodohippurate.
Nucl. Med. Commun. 24(5) , 583-95, (2003) The dimethyl ester of diethylene triamine penta-acetic acid (DMDTPA) (I) can be easily and efficiently labelled with 99mTc. This method can be readily adapted for kit formulations to produce a highly stable and very pure chelate, as shown by paper electrophor... |