4-溴-1-氟-2-硝基苯
4-溴-1-氟-2-硝基苯结构式
|
常用名 | 4-溴-1-氟-2-硝基苯 | 英文名 | 2-fluoro-5-bromonitrobenzene |
|---|---|---|---|---|
| CAS号 | 364-73-8 | 分子量 | 219.996 | |
| 密度 | 1.8±0.1 g/cm3 | 沸点 | 257.5±20.0 °C at 760 mmHg | |
| 分子式 | C6H3BrFNO2 | 熔点 | 18-19 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 109.5±21.8 °C |
|
1,5-Disubstituted benzimidazoles that direct cardiomyocyte differentiation from mouse embryonic stem cells.
Bioorg. Med. Chem. 23 , 5282-92, (2015) Cardiomyopathy is the leading cause of death worldwide. Despite progress in medical treatments, heart transplantation is one of the only current options for those with infarcted heart muscle. Stem cell differentiation technology may afford cell-based therapeu... |
|
|
Dibenzazepines and dibenzoxazepines as sodium channel blockers.
Bioorg. Med. Chem. Lett. 25(1) , 43-7, (2015) We have identified two related series of dibenzazepine and dibenzoxazepine sodium channel blockers, which showed good potency on Nav1.7 in FLIPR-based and electrophysiological functional assays. |
|
|
Synthesis and evaluation of11C-labeled naphthalene derivative as a novel non-peptidergic probe for the β-secretase (BACE1) imaging in Alzheimer's disease brain
Nucl. Med. Biol. 40(5) , 705-9, (2013) Introduction As a first trial for in vivo imaging of β-secretase (BACE1) in Alzheimer's disease brain, we applied a novel non-peptidergic small molecule which has high affinity to the enzyme, naphthalene-1-carboxylic acid (3′-chloro-4′-fluoro-4-piperazin-1-yl... |
|
|
Efficient nucleophilic aromatic substitution between aryl nitrofluorides and alkynes.
Org. Lett. 9(14) , 2741-3, (2007) The nucleophilic aromatic substitution reaction between electron-deficient aryl fluorides and terminal alkynes is shown to be efficiently promoted by sodium bis(trimethylsilyl)amide as a base. Moderate to excellent yields of 2-ethynylnitrobenzene products can... |
|
|
Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity.
J. Med. Chem. 46 , 5651-5662, (2003) We wish to report the synthesis and structure-activity relationship (SAR) of a series of 4-aminobenzophenones, as a novel compound class with high antiinflammatory activity. Our initial lead, (4-[(2-aminophenyl)amino]phenyl)(phenyl)methanone (3), was systemat... |