L-亮氨酸甲酯盐酸盐
L-亮氨酸甲酯盐酸盐结构式
|
常用名 | L-亮氨酸甲酯盐酸盐 | 英文名 | H-Leu-OMe.HCl |
|---|---|---|---|---|
| CAS号 | 7517-19-3 | 分子量 | 181.660 | |
| 密度 | 0.955 g/cm3 | 沸点 | 169.2ºC at 760 mmHg | |
| 分子式 | C7H16ClNO2 | 熔点 | 151-153 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | N/A |
|
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Nat. Chem. Biol. 5 , 45-52, (2009) Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting transceptors is unknown. We have screened 319 amino acid anal... |
|
|
Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor.
Cell Death Dis. 5 , e1409, (2014) Btk and Etk/BMX are Tec-family non-receptor tyrosine kinases. Btk has previously been reported to be expressed primarily in B cells and has an important role in immune responses and B-cell malignancies. Etk has been shown previously to provide a strong surviv... |
|
|
Primary in vitro immunization with multimeric synthetic peptides of HIV-1 envelope glycoproteins: generation of neutralizing human monoclonal antibodies.
J. Immunol. Methods 176(1) , 9-22, (1994) Peripheral blood lymphocytes from healthy HIV-1 seronegative donors were immunized in vitro with the following synthetic peptides: (i) an octameric poly-L-lysine conjugated peptide of the HIV-1MN V3 loop and (ii) a resin bound synthetic peptide aa642-665 of H... |
|
|
Conglomerate crystallization on self-assembled monolayers.
Chem. Commun. (Camb.) 47 , 12161-12163, (2011) In this communication, we demonstrate that chiral self-assembled monolayers can be used for polymorphism control of chiral crystals. We studied the crystallization of DL-glutamic acid on chiral self-assembled monolayers and showed that crystallization of DL-g... |
|
|
Kinetics of the intracellular differentiation of Leishmania amazonensis and internalization of host MHC molecules by the intermediate parasite stages.
Parasitology 122(Pt 3) , 263-79, (2001) The establishment of Leishmania in mammals depends on the transformation of metacyclic promastigotes into amastigotes within macrophages. The kinetics of this process was examined using mouse macrophages infected with metacyclic promastigotes of L. amazonensi... |
|
|
Monocytes stimulated by 110-kDa fibronectin fragments suppress proliferation of anti-CD3-activated T cells.
J. Immunol. 175(5) , 3347-53, (2005) One hundred ten to 120-kDa fragments of fibronectin (FNf), generated by proteases released in the course of tissue injury and inflammation, stimulate monocytes to produce proinflammatory cytokines, promote mononuclear leukocytes (MNL) transendothelial migrati... |
|
|
Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme.
Biochemistry 40(25) , 7453-63, (2001) The following three-dimensional structures of three forms of Escherichia coli branched-chain amino acid aminotransferase (eBCAT) have been determined by the X-ray diffraction method: the unliganded pyridoxal 5'-phosphate (PLP) form at a 2.1 A resolution, and ... |
|
|
Role of specific activators of intestinal amino acid transport in Bombyx mori larval growth and nutrition.
Arch. Insect Biochem. Physiol. 48(4) , 190-8, (2001) Nutrient absorption and its modulation are critical for animal growth. In this paper, we demonstrate that leucine methyl ester (Leu-OMe) can greatly increase the activity of the transport system responsible for the absorption of most essential amino acids in ... |
|
|
Prion protein-overexpressing cells show altered response to a neurotoxic prion protein peptide.
J. Neurosci. Res. 54(3) , 331-40, (1998) A peptide fragment of the prion protein, PrP106-126 is toxic to neuronal cells in culture. This toxicity is dependent on neuronal expression of the prion protein (PrPc) and also the presence of microglia. The role of expression of the PrPc in neurotoxicity of... |
|
|
Effect of L-leucine methyl ester on growth and ultrastructure of Trypanosoma cruzi.
Acta Trop. 101(1) , 69-79, (2007) L-Amino acid methyl esters, such as L-leucine methyl ester (Leu-OMe), have been identified as agents targeting the lysosomal system of Leishmania amazonensis amastigotes, by a mechanism that involves ester hydrolysis by parasite enzymes located inside megasom... |