alpha1-17-促肾上腺皮质激素
alpha1-17-促肾上腺皮质激素结构式
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常用名 | alpha1-17-促肾上腺皮质激素 | 英文名 | ACTH [1-17] |
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| CAS号 | 7266-47-9 | 分子量 | 2093.41000 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C95H145N29O23S | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Differences in cortisol, aldosterone and testosterone responses to ACTH 1-17 administered at two different times of day.
Chronobiologia 14(1) , 39-46, (1987) The effects of 100 micrograms, i.m. of the analog ACTH 1-17 administered at 0800 and 1800 on the secretion of cortisol, aldosterone and testosterone have been studied in normal subjects: 8 male and 8 female. The group as a whole and the males had significantl... |
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Acute and chronic effects of human recombinant GH (hrGH) on adrenal steroidogenesis in children affected with isolated GH deficiency (IGHD).
J. Clin. Endocrinol. Metab. 80(7) , 2251-4, (1995) In a previous study we demonstrated that, in children affected with isolated GH deficiency, an acute high-dose human recombinant GH (hrGH) treatment increases the 11-deoxycortisol and induces an IGF-I responsiveness to ACTH. The aim of the present study was t... |
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N-terminal ACTH fragments increase the CSF beta-EP content in Alzheimer type dementia.
Acta Neurol. Scand 78(2) , 146-51, (1988) Eleven patients with presenile Alzheimer type dementia (ATD) were treated with N-terminal ACTH fragments for 14 days. No change in cognitive functions was observed during the treatment. A significant increase in CSF beta-endorphin (beta-EP) levels was found, ... |
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Dopaminergic regulation of aldosterone secretion: assessment in different subtypes of primary aldosteronism and in essential hypertension.
J. Int. Med. Res. 19(1) , 44-9, (1991) The inhibitory effect of dopamine on aldosterone secretion was investigated in patients with different types of primary aldosteronism, six with idiopathic hyperaldosteronism (IHA) and four with dexamethasone-suppressible hyperaldosteronism (DSH), and in 10 pa... |
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Dysregulation of adrenal 11 beta-hydroxylase activity in hypertensive subjects: usefulness of the ACTH 1-17 stimulation test.
Nutr. Metab. Cardiovasc. Dis. 9(4) , 192-5, (1999) The aim of this study was to determine the validity of our previous hypothesis of adrenal 11 beta-hydroxylase (11-OH) dysregulation in "essential" low-renin hypertension.A comparison was made between 30 hypertensive patients and 30 age-matched controls (NC) i... |
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Exogenous melatonin enhances the TRH-induced prolactin release in normally cycling women: a sex-specific effect.
Gynecol. Endocrinol. 5(2) , 83-94, (1991) The aim of the present study was to analyze the effects of exogenous melatonin (MT) upon pituitary and adrenal responsiveness to releasing hormones in different phases of the menstrual cycle. We evaluated the response of FSH and LH to 100 micrograms gonadotro... |
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The effects of ACTH 1-17 on GH secretion in vitro.
Horm. Metab. Res. 19(8) , 361-3, (1987) Recently we demonstrated that ACTH 1-17 infusion in normal subjects is able to stimulate growth hormone (GH) secretion. In order to study the mechanism by which ACTH 1-17 induces this hormonal secretory pattern, we examined the effects of ACTH 1-17 addition t... |
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ACTH1-17 is a more potent agonist at the human MC1 receptor than alpha-MSH.
Cell Mol. Biol. 45(7) , 1029-34, (1999) The melanocortin receptor MC1 is expressed on melanocytes and is an important control point for melanogenesis and other responses. Alpha-MSH, which is considered to be the major ligand at the human melanocortin (MC)1 receptor (hMC1R), is produced from proopio... |
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Effect of a synthetic short-chain ACTH 1-17 (HOE 433) on isoproterenol-induced myocardial infarction in rats.
Indian J. Exp. Biol. 26(9) , 685-7, (1988)
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Circadian stage-dependent effect of ACTH and melatonin on protein synthesis by rat adrenal cells.
Braz. J. Med. Biol. Res. 21(4) , 759-62, (1988) The objective of the present study was to determine the circadian effects of melatonin and two different ACTH preparations: a synthetic heptadecapeptide with adrenocorticotrophic action (Synchrodyn 1-17, HOE 433) and a natural ACTH (Acthar, Armour). Both ACTH... |