4-甲氧基-2-萘胺
4-甲氧基-2-萘胺结构式
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常用名 | 4-甲氧基-2-萘胺 | 英文名 | 4-Methoxy-2-naphthalenamine |
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| CAS号 | 2764-95-6 | 分子量 | 173.211 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 352.9±15.0 °C at 760 mmHg | |
| 分子式 | C11H11NO | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 186.9±13.6 °C |
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Assay of dipeptidyl peptidase IV in serum by fluorometry of 4-methoxy-2-naphthylamine.
Clin. Chem. 34(11) , 2299-301, (1988) A new fluorometric assay for determining dipeptidyl peptidase IV (DPP IV; EC 3.4.14.5) was developed. The synthetic substrate glycyl-L-proline-4-methoxy-2-naphthylamide (20 mmol/L), Tris buffer (50 mmol/L, pH 8.3), and serum (20 microL) are mixed and incubate... |
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The role of the intralysosomal pH in the control of autophagic proteolytic flux in rat hepatocytes.
Eur. J. Biochem. 235(3) , 564-73, (1996) Current methods to estimate changes in intralysosomal pH in hepatocytes do not discriminate between lysosomes and other intracellular acidic compartments. To obtain selective information on the change in lysosomal function in response to a change in lysosomal... |
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Epidermal aminopeptidase activity and metabolism as observed in an organized HaCaT cell sheet model.
J. Pharm. Sci. 86(3) , 378-83, (1997) Metabolism studies on organized HaCaT keratinocyte cell sheets are reported. Cells were grown on porous membranes to form organized cell sheets of several cell layers, which were considered as a model of viable epidermis. Metabolism was studied by reflection ... |
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Neutral aminopeptidase and dipeptidyl peptidase IV activities in plasma of monosodium glutamate obese and food-deprived rats.
Obesity (Silver Spring.) 18(7) , 1312-7, (2010) Biometric parameters, glycemia and activity levels of plasma neutral aminopeptidase (APN) and dipeptidyl peptidase IV (DPPIV) were measured in monosodium glutamate obese and food-deprived rats (MSG-FD), to analyze the involvement of these enzymes in such situ... |
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Quantification of intracellular cathepsin activities in human lung tumor cell lines by flow cytometry.
Biol. Chem. Hoppe-Seyler 376(7) , 407-14, (1995) The cysteine proteases cathepsin B and cathepsin L are very likely involved in invasive processes of normal and malignant cells, they become relevant for a number of diseases and are possibly prognostic markers for the outcome of human lung cancer. Therefore,... |
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Investigation of proteinases in the digestive tract using 4-methoxy-2-naphthylamine (MNA) substrates.
J. Histochem. Cytochem. 29(3A Suppl) , 464-80, (1981) Aminopeptidase (AP) A, B, and M, gamma-glutamyltranspeptidase (GGT), endopeptidase I and II, membrane-associated endopeptidase I and II, dipeptidylaminopeptidase (DAP) I, II, and IV, trypsin and chymotrypsin were investigated with 4-methoxy-2-naphthylamine (M... |
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Comparative histochemical, biochemical and immunocytochemical studies of cathepsin B in human gingiva.
J. Periodont. Res. 29(3) , 203-13, (1994) Cathepsin B activity was demonstrated histochemically in unfixed cryostat sections of inflamed human gingiva using the 2-methoxy-4-naphthylamide (MNA) substrates Z-Val-Lys-Lys-Arg-MNA and Z-Ala-Arg-Arg-MNA with a post-azo-coupling technique. Enzyme localisati... |
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Flexibility of the coordination geometry around the cupric ions in Cu(II)-rat dipeptidyl peptidase III is important for the expression of enzyme activity.
Arch. Biochem. Biophys. 525(1) , 71-81, (2012) Dipeptidyl peptidase III (DPP III), the zinc peptidase, has a unique helix portion in the metal-binding motif (HELLGH). The enzyme activity of the cupric derivative of rat DPP III (Cu(II)-rat DPP III) for Lys-Ala-β-NA is about 30% of that of the wild-type enz... |
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Cytochemical localization and biochemical evaluation of a lysosomal serine protease in lung: dipeptidyl peptidase II in the normal rat.
J. Histochem. Cytochem. 33 , 677-686, (1985) Dipeptidyl peptidase II (DPP II) in normal rat lung was evaluated by the enzymes' ability to hydrolyze Lys-Ala or Lys-Pro derivatives of 4-methoxy-2-naphthylamine (MNA). For visualization of this activity, the liberated MNA was coupled with fast blue B for li... |