醋酸生长抑素
醋酸生长抑素结构式
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常用名 | 醋酸生长抑素 | 英文名 | Somatostatin-14 |
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| CAS号 | 38916-34-6 | 分子量 | 1637.878 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 1970.9±65.0 °C at 760 mmHg | |
| 分子式 | C76H104N18O19S2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 1145.7±34.3 °C |
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Frequency-dependent, cell type-divergent signaling in the hippocamposeptal projection.
J. Neurosci. 34(35) , 11769-80, (2014) Hippocampal oscillations are critical for information processing, and are strongly influenced by inputs from the medial septum. Hippocamposeptal neurons provide direct inhibitory feedback from the hippocampus onto septal cells, and are therefore likely to als... |
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Role of somatostatin and somatostatin receptor type 2 in postincisional nociception in rats.
Neuropeptides 49 , 47-54, (2015) Somatostatin (SST) and the somatostatin receptor type 2 (sstr2) are expressed in the superficial part (Laminae I-III) of the dorsal horn of the spinal cord. Since the neurons in these laminae also receive nociceptive sensation from the periphery, it was hypot... |
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Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration.
BMC Biol. 13 , 70, (2015) In contrast to mammals, the zebrafish has the remarkable capacity to regenerate its pancreatic beta cells very efficiently. Understanding the mechanisms of regeneration in the zebrafish and the differences with mammals will be fundamental to discovering molec... |
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Differential levels of Neurod establish zebrafish endocrine pancreas cell fates.
Dev. Biol. 402 , 81-97, (2015) During development a network of transcription factors functions to differentiate foregut cells into pancreatic endocrine cells. Differentiation of appropriate numbers of each hormone-expressing endocrine cell type is essential for the normal development of th... |
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Aging, but not tau pathology, impacts olfactory performances and somatostatin systems in THY-Tau22 mice.
Neurobiol. Aging 36(2) , 1013-28, (2015) Somatostatin (SOM) cortical levels decline in Alzheimer's disease (AD) in correlation with cognitive impairment severity, the latter being closely related to the presence of neurofibrillary tangles. Impaired olfaction is another hallmark of AD tightly related... |
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Perineuronal nets affect parvalbumin expression in GABAergic neurons of the mouse hippocampus.
Eur. J. Neurosci. 41(3) , 368-78, (2015) Recent studies have suggested that the perineuronal net (PNN), a specialised extracellular matrix structure, and parvalbumin (PV), an EF-hand calcium-binding protein, are involved in the regulation of plasticity of neural circuits. Here, we aimed to quantitat... |
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The contribution of raised intraneuronal chloride to epileptic network activity.
J. Neurosci. 35 , 7715-26, (2015) Altered inhibitory function is an important facet of epileptic pathology. A key concept is that GABAergic activity can become excitatory if intraneuronal chloride rises. However, it has proved difficult to separate the role of raised chloride from other contr... |
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Correlations between Photodegradation of Bisretinoid Constituents of Retina and Dicarbonyl Adduct Deposition.
J. Biol. Chem. 290 , 27215-27, (2015) Non-enzymatic collagen cross-linking and carbonyl adduct deposition are features of Bruch's membrane aging in the eye, and disturbances in extracellular matrix turnover are considered to contribute to Bruch's membrane thickening. Because bisretinoid constitue... |
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Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species.
Endocrinology 156(4) , 1540-51, (2015) Na+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the first and rate-limiting step in the biosynthesis of the thyroid hormones. The expression and function of NIS in thyroid cells is mainly regulated by TSH and by the intracellular conc... |
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Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina.
J. Neurosci. 35 , 15955-70, (2015) An inner retinal microcircuit composed of dopamine (DA)-containing amacrine cells and melanopsin-containing, intrinsically photosensitive retinal ganglion cells (M1 ipRGCs) process information about the duration and intensity of light exposures, mediating lig... |