7,7-二甲基二十碳二烯酸
7,7-二甲基二十碳二烯酸结构式
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常用名 | 7,7-二甲基二十碳二烯酸 | 英文名 | 7,7-dimethyleicosadienoic acid |
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| CAS号 | 89560-01-0 | 分子量 | 336.55200 | |
| 密度 | 0.9g/cm3 | 沸点 | 456.1ºC at 760 mmHg | |
| 分子式 | C22H40O2 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 352.7ºC |
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Exocytosis in chromaffin cells: evidence for a MgATP-independent step that requires a pertussis toxin-sensitive GTP-binding protein.
Biochem. J. 15 , 217-227, (1994) We have previously described that mastoparan, an amphiphilic tetradecapeptide that activates heterotrimeric G-proteins, inhibits Ca(2+)-induced MgATP-dependent secretion from streptolysin-O-permeabilized chromaffin cells [Vitale, Mukai, Rouot, Thiersé, Aunis ... |
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Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
Brain Res. 844 , 1-9, (1999) In an evaluation of the contribution of swelling-induced amino acid release, through the regulatory volume decrease (RVD) process, to cerebral ischemic injury, studies of the role of phospholipases and protein kinases in the response to hyposmotic stress were... |
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Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease.
Neurochem. Res. 28(2) , 319-26, (2003) In this paper we show that exposure of a rat brain synaptosome fraction to the amyloid beta peptide fragment betaA(25-35), but not the inverted peptide betaA(35-25), stimulated production of reactive oxygen species (ROS) in a concentration- and time-dependent... |
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Phospholipase A2 is not responsible for lysophosphatidylcholine-induced damage in cardiomyocytes.
Am. J. Physiol. 275(5 Pt 2) , H1782-7, (1998) Lysophosphatidylcholine (LPC) is known to increase the intracellular concentration of Ca2+ ([Ca2+]i), leading to cell damage. In the present study we examined whether LPC activates phospholipase A2 (PLA2) and whether the activation of PLA2 is responsible for ... |
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The effects of two phospholipase A2 inhibitors on the neuromuscular blocking activities of homologous phospholipases A2 from the venom of Pseudechis australis, the Australian king brown snake.
Toxicon 33(12) , 1633-43, (1995) Previous studies have shown that homologous phospholipases A2 (PLA2) (Pa-3, Pa-9C, Pa-10F and Pa-11) from the venom of the Australian king brown snake, Pseudechis australis, significantly reduce the resting membrane potentials and quantal contents of endplate... |
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Endothelin-induced prostacyclin production in rat aortic rings is mediated by protein kinase C.
Prostaglandins Leukot. Essent. Fatty Acids 55(5) , 309-13, (1996) Endothelin (ET) is a vasoconstrictor peptide released from endothelial cells that is known to cause prostaglandin release. The mechanism remains unclear. To determine whether the protein kinase C (PKC) signaling pathway is stimulated by endothelin, we pretrea... |
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Light activation of phospholipase A2 in the photoreceptor of the crayfish (Procambarus clarkii).
Acta Neurobiol. Exp. (Wars) 60(1) , 9-16, (2000) Retinal lipids of crayfish, kept at 4 degrees C under continuous darkness for 3 weeks, consisted mainly of phosphatidylcholine (PC) and phosphatidylethanolamine (PE); sphingomyelin (SM), phosphatidylinositol (PI) and phosphatidylserine (PS) were minor contrib... |
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The polychlorinated biphenyl mixture aroclor 1254 induces death of rat cerebellar granule cells: the involvement of the N-methyl-D-aspartate receptor and reactive oxygen species.
Toxicol. Appl. Pharmacol. 179(3) , 137-44, (2002) Polychlorinated biphenyls (PCBs) are widespread persistent environmental contaminants that display a complex spectrum of toxicological properties, including neurotoxicity. The present study investigates the effects of the PCB mixtures Aroclor 1242 (A1242) and... |
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Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA).
J. Biol. Chem. 283(37) , 25428-36, (2008) Phospholipases A(2) (PLA(2)s) catalyze hydrolysis of fatty acids from the sn-2 position of phospholipids. Here we report the identification and characterization of a membrane-associated intracellular calcium-dependent, adipose-specific PLA(2) that we named Ad... |
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Effects of the solvent 1,2,4-trimethylcyclohexane on respiratory burst in human neutrophil granulocytes. A chemiluminescence and electron paramagnetic resonance spectrometry study.
Ann. N. Y. Acad. Sci. 893 , 358-61, (1999)
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