积雪草苷
积雪草苷结构式
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常用名 | 积雪草苷 | 英文名 | Asiaticoside |
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| CAS号 | 16830-15-2 | 分子量 | 959.12 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 949.4±65.0 °C at 760 mmHg | |
| 分子式 | C48H78O19 | 熔点 | 235-238ºC | |
| MSDS | 中文版 美版 | 闪点 | 268.4±27.8 °C |
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In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica.
J. Ethnopharmacol. 130(2) , 275-83, (2010) Centella asiatica (CA) has been widely cultivated as a vegetable or spice in China, Southeast Asia, India, Sri Lanka, Africa, and Oceanic countries and traditionally used for wound healing and maintaining normal blood pressure.The present study was carried ou... |
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Factors affecting the content of pentacyclic triterpenes in Centella asiatica raw materials.
Pharm. Biol. 50(12) , 1508-12, (2012) Pentacyclic triterpenes, mainly, asiatic acid, madecassic acid, asiaticoside, and madecassoside are the active constituents of Centella asitica (L.) Urban. (Apiaceae). These compounds possess various pharmacological activities that have been shown to assist w... |
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Matrix metalloproteinase, hyaluronidase and elastase inhibitory potential of standardized extract of Centella asiatica.
Pharm. Biol. 51(9) , 1182-7, (2013) Centella asiatica (L.) Urban (Apiaceae), a valuable herb described in Ayurveda, is used in the indigenous system of medicine as a tonic to treat skin diseases.Centella asiatica methanol extract and its ethyl acetate, n-butanol and aqueous fraction, were subje... |
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An ethnopharmacological study on Verbascum species: from conventional wound healing use to scientific verification.
J. Ethnopharmacol. 132(2) , 408-13, (2010) The leaves, flowers, and whole aerial parts of Verbascum L. (Scrophulariaceae) species are used to treat eczema and other types of inflammatory skin conditions and as a desiccant for wounds in Turkish traditional medicine. In the present study, the methanolic... |
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Asiaticoside induces type I collagen synthesis and osteogenic differentiation in human periodontal ligament cells.
Phytother Res. 27(3) , 457-62, (2013) Asiaticoside, an active ingredient extracted from Centella asiatica, has been widely used to promote wound healing. In this study, the effects of asiaticoside on proliferation, protein synthesis, and osteogenic differentiation in human periodontal ligament ce... |
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Investigating wound healing, tyrosinase inhibitory and antioxidant activities of the ethanol extracts of Salvia cryptantha and Salvia cyanescens using in vivo and in vitro experimental models.
J. Ethnopharmacol. 135(1) , 71-7, (2011) Salvia L. species are widely used against wounds and skin infections in Turkish folk medicine.The aim of the present study is to evaluate wound healing activity of the ethanol (EtOH) extracts of Salvia cryptantha and Salvia cyanescens.For the assessment of wo... |
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Protective effects of asiaticoside on septic lung injury in mice.
Exp. Toxicol. Pathol. 63(6) , 519-25, (2011) Asiaticoside (AS), a major triterpenoid saponin component isolated from Centella asiatica, has been described to exhibit antioxidant and anti-inflammatory activities. The present study aimed to determine the protective effects and the underlying mechanisms of... |
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Asiaticoside induces tumour-necrosis-factor-α-mediated nitric oxide production to cure experimental visceral leishmaniasis caused by antimony-susceptible and -resistant Leishmania donovani strains.
J. Antimicrob. Chemother. 67(4) , 910-20, (2012) The aim of this study was to investigate and characterize the efficacy of asiaticoside in an experimental model of visceral leishmaniasis caused by antimony-susceptible (AG83) and -resistant (GE1F8R and K39) Leishmania donovani.The effect of asiaticoside was ... |
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New alternative therapy for orofacial localized scleroderma.
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 110(3) , e15-9, (2010)
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In vitroinhibitory effects of asiaticoside and madecassoside on human cytochrome P450
Toxicol. In Vitro 25(4) , 890-6, (2011) The inhibitory effects and types of inhibition of asiaticoside and madecassoside on human CYPs were studied in vitro using recombinant human CYPs. The median inhibitory concentrations (IC 50) of asiaticoside and madecassoside were determined for CYP1A2, CYP2C... |