双十六烷基磷酸
双十六烷基磷酸结构式
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常用名 | 双十六烷基磷酸 | 英文名 | Dicetylphosphate |
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| CAS号 | 2197-63-9 | 分子量 | 546.846 | |
| 密度 | 0.9±0.1 g/cm3 | 沸点 | 600.4±38.0 °C at 760 mmHg | |
| 分子式 | C32H67O4P | 熔点 | 74-75ºC(lit.) | |
| MSDS | 美版 | 闪点 | 316.9±26.8 °C |
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Fungal recognition enhances mannose receptor shedding through dectin-1 engagement.
J. Biol. Chem. 286(10) , 7822-9, (2011) The mannose receptor (MR) is an endocytic type I membrane molecule with a broad ligand specificity that is involved in both hemostasis and pathogen recognition. Membrane-anchored MR is cleaved by a metalloproteinase into functional soluble MR (sMR) composed o... |
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The effect of nanoliposomal formulations on Staphylococcus epidermidis biofilm.
Drug Dev. Ind. Pharm. 41(3) , 445-50, (2015) The aim of the present study was to assess the in vitro antimicrobial activities of nanoliposomal formulations loaded with vancomycin or/and rifampin against the biofilm formed by Staphylococcus epidermidis at 37 °C under aerobic condition.Liposomal formulati... |
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Liposome, gel and lipogelosome formulations containing sodium hyaluronate.
J. Liposome Res. 24(4) , 259-69, (2014) The moisture-imparting effect of sodium hyaluronate (Na-HA) was investigated in liposome, gel and lipogelosome topical formulations. Sixteen liposome formulations were prepared with or without Na-HA (45 kDa) using various ratios of dimyristoylphosphatidylchol... |
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Ultrasound effects on brain-targeting mannosylated liposomes: in vitro and blood-brain barrier transport investigations.
Drug Des. Devel. Ther. 9 , 3885-98, (2015) Delivering drugs to intracerebral regions can be accomplished by improving the capacity of transport through blood-brain barrier. Using sertraline as model drug for brain targeting, the current study aimed at modifying its liposomal vesicles with mannopyranos... |
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Development and characterization of mixed niosomes for oral delivery using candesartan cilexetil as a model poorly water-soluble drug.
AAPS PharmSciTech 16(1) , 108-17, (2015) The aim of this study was to prepare candesartan cilexetil-loaded niosomes and mixed niosomes to enhance the aqueous solubility of the drug, thus improving its oral bioavailability. The formulations were prepared using various types and combinations of surfac... |
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Paclitaxel-loaded niosomes for intravenous administration: pharmacokinetics and tissue distribution in rats.
Turk. J. Med. Sci. 45 , 1403-12, (2016) The purpose of this study was to investigate and compare the pharmacokinetic behavior and tissue distribution of paclitaxel, delivered as commercial preparation Taxol or through Span 40 niosomes, after intravenous injection to rats.Paclitaxel-loaded Span 40 n... |
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Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2.
J. Lipid Res. 55(12) , 2606-19, (2014) During endocytosis, membrane components move to intraluminal vesicles of the endolysosomal compartment for digestion. At the late endosomes, cholesterol is sorted out mainly by two sterol-binding proteins, Niemann-Pick protein type C (NPC)1 and NPC2. To study... |
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Nano-transfersomal ciprofloxacin loaded vesicles for non-invasive trans-tympanic ototopical delivery: in-vitro optimization, ex-vivo permeation studies, and in-vivo assessment.
Int. J. Pharm. 472(1-2) , 304-14, (2014) Ciprofloxacin is a synthetic fluoroquinolone antibiotic that has been used for systemic treatment of otitis media in adults. It was approved for topical treatment of otorrhea in children with tympanostomy tubes. The aim of this work was to enhance the local n... |
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Thermal and 31P-NMR studies to elucidate sumatriptan succinate entrapment behavior in phosphatidylcholine/cholesterol liposomes. Comparative 31P-NMR analysis on negatively and positively-charged liposomes.
Colloids Surf. B Biointerfaces 105 , 14-23, (2013) In this paper, two techniques, differential scanning calorimetry (DSC) and phosphorus nuclear magnetic resonance ((31)P-NMR), have been used to characterize sumatriptan succinate-loaded charged liposomes. To complete the results obtained by DSC a hot stage mi... |
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Preparation and characterization of nitrendipine solid lipid nanoparticles.
Pharmazie 66(3) , 178-86, (2011) Nitrendipine, a dihydropyridine calcium channel blocker, has very poor oral bioavailability (10-20%) due to first pass effect. Solid lipid nanoparticle (SLN) delivery systems of nitrendipine have been developed using various triglycerides (trimyristin, tripal... |