6,7-二甲氧基-3,4-二氢-2H-1-萘酮
6,7-二甲氧基-3,4-二氢-2H-1-萘酮结构式
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常用名 | 6,7-二甲氧基-3,4-二氢-2H-1-萘酮 | 英文名 | 6,7-Dimethoxy-3,4-dihydronaphthalen-1(2H)-one |
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| CAS号 | 13575-75-2 | 分子量 | 206.23800 | |
| 密度 | 1.14g/cm3 | 沸点 | 358.3ºC at 760mmHg | |
| 分子式 | C12H14O3 | 熔点 | 98-100 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 161.8ºC |
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Synthesis and dopaminergic activity of 2-substituted octahydrobenzo[f]quinolines.
J. Med. Chem. 32 , 961, (1989) A series of 2-substituted octahydrobenzo[f]quinolines has been synthesized and assayed for dopamine agonist activity. Only the compounds corresponding to the beta-rotameric conformation of dopamine showed biphasic activity in competition binding studies with ... |
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Substituted benz[a]acridines and benz[c]acridines as mammalian topoisomerase poisons.
Bioorg. Med. Chem. 8(5) , 1171-82, (2000) Coralyne and several other synthetic benzo[a,g]quinolizium derivatives related to protoberberine alkaloids have exhibited activity as topoisomerase poisons. These compounds are characterized by the presence of a positively charged iminium group, which has bee... |
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J. Org. Chem. 57 , 5907, (1992)
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2-substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity.
J. Med. Chem. 33 , 360, (1990) The synthesis, biological evaluation, and structure-activity relationships of a series of 1-naphthols bearing carbon substituents at the 2-position are described. These compounds are potent inhibitors of the 5-lipoxygenase from RBL-1 cells and also inhibit bo... |
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2-Aminotetralones: novel inhibitors of MurA and MurZ.
Bioorg. Med. Chem. Lett. 18(5) , 1730-4, (2008) Several 2-aminotetralones were identified as novel inhibitors of the bacterial enzymes MurA and MurZ. A number of these inhibitors demonstrated antibacterial activity against Staphylococcus aureus and Escherichia coli with MICs in the range 8-128 microg/ml. B... |