H-Leu-Leu-OMe·HCl
H-Leu-Leu-OMe·HCl结构式
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常用名 | H-Leu-Leu-OMe·HCl | 英文名 | L-Leucyl-L-Leucine methyl ester hydrobromide |
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| CAS号 | 16689-14-8 | 分子量 | 339.26900 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C13H27BrN2O3 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Inhibition of L-leucine methyl ester mediated killing of THP-1, a human monocytic cell line, by a new anti-inflammatory drug, T614.
Immunopharmacology 49 , 285-294, (2000) T614 (3-formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-o ne) is a member of the family of methanesulfonanilide non-steroidal anti-inflammatory drugs (mNSAIDs), most of which act as cyclooxygenase (COX)-2 inhibitors. L-leucine methyl ester (Leu-... |
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Engraftment capacity of mesenchymal cells following hematopoietic stem cell transplantation in patients receiving reduced-intensity conditioning regimen.
Leukemia 20 , 329-335, (2006) The engraftment ability of mesenchymal cells was investigated in 26 patients receiving allogeneic transplantation from HLA-identical siblings with reduced-intensity conditioning (RIC). The stem cell source was bone marrow (BM) in eight patients and G-CSF-mobi... |
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Use of granzyme B-based fluorescent protein reporters to monitor granzyme distribution and granule integrity in live cells.
Biol. Chem. 391 , 999-1004, (2010) Reporter proteins comprising granzyme B (GrB) fused to eGFP, ecliptic pHluorin or mCherry, were generated and used to study granule (lysosome) distribution and properties in COS-1 cells and natural killer cells. The reporters resembled native GrB in biosynthe... |
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Lysosomal membrane permeabilization induces cell death in human mast cells.
Scand. J. Immunol. 74 , 354-362, (2011) Mast cells (MC) have pathogenic roles in numerous disorders, and strategies that stabilize MC or induce MC apoptosis are therefore emerging as possible therapeutic regimens. A typical feature of MC is their high content of secretory lysosomes (granules), cont... |
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Synthesis, photoreactivity and cytotoxic activity of caged compounds of L-leucyl-L-leucine methyl ester, an apoptosis inducer.
Photochem. Photobiol. 63 , 800-806, (1996) L-Leucyl-L-leucine methyl ester (Leu-Leu-OMe), an apoptosis inducer in natural killer cells and macrophages, was caged with trans-o-hydroxycinnamoyl (3a-d), trans-o-mercaptocinnamoyl (4) and o-nitrobenzyl derivatives (5a, b), and the photochemical reactivity ... |
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Thiele, D.L. and Lipsky, P.E.
Fed. Proc. 44 , 590, (1985)
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