12-溴十二烷酸
12-溴十二烷酸结构式
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常用名 | 12-溴十二烷酸 | 英文名 | 12-Bromododecanoic Acid |
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| CAS号 | 73367-80-3 | 分子量 | 279.21400 | |
| 密度 | 1.191 g/cm3 | 沸点 | 367.8ºC at 760 mmHg | |
| 分子式 | C12H23BrO2 | 熔点 | 52-55 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | >230 °F |
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12-Bromododecanoic acid binds inside the calyx of bovine beta-lactoglobulin.
FEBS Lett. 438(3) , 272-8, (1998) The X-ray structure of bovine beta-lactoglobulin with the ligand 12-bromododecanoic acid as a model for fatty acids has been determined at a resolution of 2.23 A in the trigonal lattice Z form. The ligand binds inside the calyx, resolving a long-standing cont... |
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Calibration of the channel that determines the omega-hydroxylation regiospecificity of cytochrome P4504A1: catalytic oxidation of 12-HALODOdecanoic acids.
J. Biol. Chem. 280(24) , 22697-705, (2005) The fatty acid omega-hydroxylation regiospecificity of CYP4 enzymes may result from presentation of the terminal carbon to the oxidizing species via a narrow channel that restricts access to the other carbon atoms. To test this hypothesis, the oxidation of 12... |
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NMR studies of substrate binding to cytochrome P450 BM3: comparisons to cytochrome P450 cam.
Biochemistry 34(28) , 8982-8, (1995) The binding of the substrates sodium laurate and sodium 12-bromolaurate to the heme-containing domain of Bacillus megaterium cytochrome P450 BM3 (CYP102) has been studied by measurement of the relaxation effects of the unpaired electrons of the heme iron on t... |
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A simple synthesis of bromine-77-labeled alkyl bromides.
Int. J. Appl. Radiat. Isot. 33(5) , 391-2, (1982)
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The other kind of biological NMR--studies of enzyme-substrate interactions.
Neurochem. Res. 21(9) , 1117-24, (1996) NMR spectroscopy has proved to be a valuable tool in the study of the interactions between enzymes and their substrates. The kinds of structural and dynamic information which can be obtained are illustrated by studies of three enzymes involved in drug metabol... |