牛奶树碱
牛奶树碱结构式
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常用名 | 牛奶树碱 | 英文名 | HISPIDIN |
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| CAS号 | 555-55-5 | 分子量 | 246.21500 | |
| 密度 | 1.657g/cm3 | 沸点 | 554.2ºC at 760 mmHg | |
| 分子式 | C13H10O5 | 熔点 | 312-315ºC | |
| MSDS | 中文版 美版 | 闪点 | 220.1ºC |
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Anti-inflammatory activity of mushroom-derived hispidin through blocking of NF-κB activation.
J. Sci. Food Agric. 95 , 2482-6, (2015) Hispidin, a polyphenol compound mainly derived from the valuable medicinal mushroom Phellinus species, has been found to possess distinct biological effects. However, the anti-inflammatory potential of hispidin still remains uncharacterized.In this study, the... |
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Anticancer activity of hispidin via reactive oxygen species-mediated apoptosis in colon cancer cells.
Anticancer Res. 34(8) , 4087-93, (2014) Few studies have been performed on the anticancer activity of hispidin, a phenolic compound produced from the medicinal mushroom Phellinus linteus. Herein, we studied hispidin-induced apoptosis, which is associated with the generation of reactive oxygen speci... |
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The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway.
Exp. Cell Res. 327(2) , 264-75, (2014) Hispidin, a phenolic compound from Phellinus linteus (a medicinal mushroom), has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties. However, the cardioprotective efficacy of hispidin has not yet been investiga... |
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Hispidin analogs from the mushroom Inonotus xeranticus and their free radical scavenging activity.
Bioorg. Med. Chem. Lett. 16 , 2376-9, (2006) Three new free radical scavengers were isolated from the methanolic extract of the fruiting bodies of Inonotus xeranticus (Hymenochaetaceae), along with the known compound davallialactone. Their structures were established as hispidin analogs by extensive NMR... |
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Highly oxygenated and unsaturated metabolites providing a diversity of hispidin class antioxidants in the medicinal mushrooms Inonotus and Phellinus.
Bioorg. Med. Chem. 15 , 3309-14, (2007) Three new highly oxygenated and unsaturated metabolites named interfungins A (1), B (2), and C (3), which provide a diversity of hispidin class compounds in the fungi Inonotus and Phellinus, were isolated from the methanolic extract of the fruiting body of th... |
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Peroxidase-mediated formation of the fungal polyphenol 3,14'-bihispidinyl.
J. Microbiol. Biotechnol. 18(1) , 107-9, (2008) Medicinal fungi, Phellinus linteus and Inonotus xeranticus, produce a cluster of yellow pigment in their fermentation broth that acts as an important element of biological activity. The pigment is composed of diverse polyphenols with a styrylpyrone moiety, ma... |
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PKC-β activation and pharmacologically induced weight gain during antipsychotic treatment.
Pharmacogenomics 12(4) , 453-5, (2011)
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Hispidin produced from Phellinus linteus protects against peroxynitrite-mediated DNA damage and hydroxyl radical generation.
Chem. Biol. Interact. 199(3) , 137-42, (2012) Oxidative stress plays an important role in the progression of many chronic diseases including cardiovascular diseases, diabetes, cancer and neurodegenerative disorders. One such mediator of oxidative stress is peroxynitrite, which is highly toxic to cultured... |
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Inhibition of low-density lipoprotein oxidation and oxidative burst in polymorphonuclear neutrophils by caffeic acid and hispidin derivatives isolated from sword brake fern (Pteris ensiformis Burm.).
J. Agric. Food Chem. 55(26) , 10579-84, (2007) Several antioxidant compounds have been previously identified from sword brake fern (Pteris ensiformis Burm.) by DPPH bleaching and Trolox equivalent antioxidant capacity (TEAC) analyses. Among the isolates, 7-O-caffeoylhydroxymaltol 3-O-beta-D-glucopyranosid... |
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Oxidative stress response of Inonotus obliquus induced by hydrogen peroxide.
Med. Mycol 47(8) , 814-23, (2009) While the medicinal fungus Inonotus obliquus produces polyphenols as one of its main metabolites in natural habitats, it accumulates less polyphenols under laboratory conditions. In this study we found that the continuous addition of 1 mM H(2)O(2) at a rate o... |