α-羟基马尿酸
α-羟基马尿酸结构式
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常用名 | α-羟基马尿酸 | 英文名 | alpha-hydroxyhippuric acid |
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| CAS号 | 16555-77-4 | 分子量 | 195.17200 | |
| 密度 | 1.325g/cm3 | 沸点 | 331.83°C (rough estimate) | |
| 分子式 | C9H9NO4 | 熔点 | 211ºC (dec.)(lit.) | |
| MSDS | 美版 | 闪点 | N/A |
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Bifunctional peptidylglcine alpha-amidating enzyme requires two copper atoms for maximum activity.
Arch. Biochem. Biophys. 311(1) , 191-5, (1994) The conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides occurs in two distinct reactions, both of which are catalyzed by bifunctional peptidylglycine alpha-amidating enzyme. The first step is the alpha-hydroxylation of the... |
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Amidation of bioactive peptides: the structure of the lyase domain of the amidating enzyme.
Structure 17(7) , 965-73, (2009) Many neuropeptides and peptide hormones require amidation of their carboxy terminal for full biological activity. The enzyme peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL; EC 4.3.2.5) catalyzes the second and last step of this reaction, N-dealkylat... |
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A novel enzyme from bovine neurointermediate pituitary catalyzes dealkylation of alpha-hydroxyglycine derivatives, thereby functioning sequentially with peptidylglycine alpha-amidating monooxygenase in peptide amidation.
Biochemistry 29(26) , 6115-20, (1990) We report here the isolation of a novel enzyme from bovine neurointermediate pituitary which catalyzes the conversion of alpha-hydroxybenzoylglycine to benzamide. This enzyme, termed HGAD (alpha-hydroxyglycine amidating dealkylase), is a soluble protein with ... |
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Urinary metabolite variation is associated with pathological progression of the post-hepatitis B cirrhosis patients.
J. Proteome Res. 11(7) , 3838-47, (2012) Cirrhosis is a common and terminal outcome of many chronic liver conditions. A urinary metabonomic study using gas chromatography-mass spectrometry (GC-MS) and ultra performance liquid chromatography time-of-flight mass spectrometry (UPLC-TOFMS) was carried o... |