甲磺酸加贝酯
甲磺酸加贝酯结构式
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常用名 | 甲磺酸加贝酯 | 英文名 | Gabexate mesylate |
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| CAS号 | 56974-61-9 | 分子量 | 417.477 | |
| 密度 | N/A | 沸点 | 508.6ºC at 760 mmHg | |
| 分子式 | C17H27N3O7S | 熔点 | 91 °C | |
| MSDS | 中文版 | 闪点 | 261.4ºC |
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Involvement of proteinase activated receptor-2 in the vascular response to sphingosine 1-phosphate.
Clin. Sci. 126(8) , 545-56, (2014) S1P (sphingosine 1-phosphate) represents one of the key latest additions to the list of vasoactive substances that modulate vascular tone. PAR-2 (proteinase activated receptor-2) has been shown to be involved in cardiovascular function. In the present study, ... |
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Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats.
Pain 152(8) , 1777-88, (2011) Gout is characterized by the deposition of monosodium urate (MSU) crystals. Despite being one of the most painful forms of arthritis, gout and the mechanisms responsible for its acute attacks are poorly understood. In the present study, we found that MSU caus... |
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Neonatal amygdala lesions advance pubertal timing in female rhesus macaques.
Psychoneuroendocrinology 51 , 307-17, (2014) Social context influences the timing of puberty in both humans and nonhuman primates, such as delayed first ovulation in low-ranking rhesus macaques, but the brain region(s) mediating the effects of social context on pubertal timing are unknown. The amygdala ... |
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The short term satiety peptide cholecystokinin reduces meal size and prolongs intermeal interval.
Peptides 32(6) , 1289-95, (2011) Camostat mesilate (or mesylate) releases endogenous cholecystokinin (CCK) or CCK-58, the only detectable endocrine form of CCK in the rat, and reduces cumulative food intake by activating CCK(1) receptor. However, the literature lacks meal pattern analysis an... |
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Effect of a serine protease inhibitor on the progression of chronic renal failure.
Am. J. Physiol. Renal Physiol. 303(8) , F1126-35, (2012) The number of the chronic renal failure (CRF) patients is increasing explosively. Hypertension, proteinuria, inflammation, fibrosis, and oxidative stress are intertwined in a complicated manner that leads to the progression of CRF. However, the therapeutic st... |
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Prospective comparative study of endoscopic papillary large balloon dilation and endoscopic sphincterotomy for removal of large bile duct stones in patients above 45 years of age.
Scand. J. Gastroenterol. 47(8-9) , 1071-7, (2012) Although endoscopic papillary large balloon dilation (EPLBD) with limited endoscopic sphincterotomy (ES) showed excellent outcomes for treatment of large bile duct stones, hemorrhage and recurrence of stones are problematic complications. Recent studies sugge... |
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Effects of antithrombin and gabexate mesilate on disseminated intravascular coagulation: a preliminary study.
Am. J. Emerg. Med. 30(7) , 1219-23, (2012) We hypothesized that antithrombin is more effective for disseminated intravascular coagulation (DIC) than is gabexate mesilate, which is a protease inhibitor, suggested from the previous studies. Initially, we compared the effects of antithrombin and gabexate... |
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The antifibrotic effect of a serine protease inhibitor in the kidney.
Am. J. Physiol. Renal Physiol. 305(2) , F173-81, (2013) Interstitial fibrosis is a final common pathway for the progression of chronic kidney diseases. Activated fibroblasts have an extremely important role in the progression of renal fibrosis, and transforming growth factor (TGF)-β₁ is a major activator of fibrob... |
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Duodenal myotomy blocks reduction of meal size and prolongation of intermeal interval by cholecystokinin.
Physiol. Behav. 105(3) , 829-34, (2012) We have shown that vagotomy (VGX) attenuates the reduction of meal size (MS) produced by cholecystokinin (CCK) -8 and -33 and that celiaco-mesenteric ganglionectomy (CMGX) attenuates the prolongation of the intermeal interval (IMI) produced by CCK-33. Here, w... |
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The Effects of Gabexate Mesilate on the Microsurgical Reconstruction of the Hepatic Artery in Living Donor Liver Transplantation
Transplant. Proc. 42(10) , 4158-60, (2010) Objectives Microsurgical reconstruction of hepatic artery is essential but require challenging techniques especially for living donor liver transplantation (LDLT), because the recipient artery is short, located deep, and usable vessel grafts are limited. Furt... |