脯氨酸-Arg-7-酰胺基-4-甲基香豆素
脯氨酸-Arg-7-酰胺基-4-甲基香豆素结构式
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常用名 | 脯氨酸-Arg-7-酰胺基-4-甲基香豆素 | 英文名 | H-Pro-Phe-Arg-AMC acetate salt |
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| CAS号 | 65147-21-9 | 分子量 | 575.65900 | |
| 密度 | 1.39g/cm3 | 沸点 | N/A | |
| 分子式 | C30H37N7O5 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates.
Meth. Enzymol. 80 , 341, (1981)
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New fluorogenic substrates for alpha-thrombin, factor Xa, kallikreins, and urokinase.
J. Biochem. Tokyo 82 , 1495, (1977) Twenty peptide-4-methylcoumarin amides (MCA) were newly synthesized and tested as possible substrates for alpha-thrombin, factor Xa, kallikreins, urokinase, and plasmin. These fluorogenic peptides contained arginine-MCA as the carboxyl-terminus. Release of 7-... |
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Coagulation factor XII protease domain crystal structure.
J. Thromb. Haemost. 13(4) , 580-91, (2015) Coagulation factor XII is a serine protease that is important for kinin generation and blood coagulation, cleaving the substrates plasma kallikrein and FXI.To investigate FXII zymogen activation and substrate recognition by determining the crystal structure o... |
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Purification and properties of rat stomach kallikrein.
Biochim. Biophys. Acta 614(2) , 501-10, (1980) Kallikrein (EC 3.4.21.8) was purified from rat stomach by column chromatography on p-aminobenzamidine-Sepharose, DEAE-Sephadex A-50 and Sephadex G-150 and by isoelectric focusing, measuring its activities to hydrolyse L-prolyl-L-phenylalanyl-L-arginine-4-meth... |
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Purification of porcine pancreatic kallikrein using various affinity chromatographies and intestinal absorption of the purified kallikrein.
Adv. Exp. Med. Biol. 156 , 469-79, (1983) For the simple purification of porcine pancreas kallikrein, various affinity chromatographies using L-prolyl-L-phenylalanyl-L-arginine (Pro-Phe-Arg-OH), tosyl-L-arginine (Tos-Arg-OH) and acetyl-L-phenylalanyl-L-arginine (Ac-Phe-Arg-OH) as ligands were examine... |
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A new fluorogenic substrate method for the estimation of kallikrein in urine.
J. Biochem. 87(4) , 1127-32, (1980) Kallikrein in human urine was measured using a fluorogenic peptide substrate, proly-phenyl-alanyl-arginine-4-methylcoumaryl-7-amide (Pro-Phe-Arg-MCA). Using 20 microliters of normal urine, kallikrein activity was quantitatively assayed by incubation with a fi... |
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Characterization of thyroglobulin-directed and polyreactive catalytic antibodies in autoimmune disease.
J. Immunol. 159(3) , 1530-6, (1997) Polyreactive and thyroglobulin (Tg)-directed proteolytic activities present in the serum IgG of healthy controls and patients with autoimmune disease were studied by electrophoretic separation of 125I-labeled Tg reaction products and spectrofluorometric measu... |
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VIPase autoantibodies in Fas-defective mice and patients with autoimmune disease.
FASEB J. 17(6) , 628-35, (2003) The immunoregulatory neuropeptide vasoactive intestinal peptide (VIP) was cleaved by purified IgG from Fas-defective C3H/gld mice, lupus patients, and autoimmune thyroiditis patients. No VIPase activity was detected in IgG from control mice and humans. Kineti... |
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Characterization of the hatching enzyme from embryos of an anuran amphibian, Rana pirica.
Biochim. Biophys. Acta 1387(1-2) , 153-64, (1998) The culture medium in which prehatching embryos of the frog, Rana pirica, were cultured (hatching medium) solubilized the vitelline coat (VC) of unfertilized eggs and contained molecules reactive to antibodies (anti-UVS.2) against the Xenopus hatching enzyme ... |
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The purification of human urinary kallikrein with ion-exchange radial flow membrane chromatography.
Biomed. Chromatogr. 10(3) , 139-43, (1996) A method was developed for the purification of kallikrein from human urine. The procedure consisted of three steps: ultradialysis, diethyl-(2-hydroxypropyl) aminoethyl (QAE) ion exchange radial flow membrane chromatography and affinity chromatography on aprot... |