二十四酸色酰胺
二十四酸色酰胺结构式
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常用名 | 二十四酸色酰胺 | 英文名 | tetracosanoic acid tryptamide |
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| CAS号 | 152766-94-4 | 分子量 | 510.83700 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C34H58N2O | 熔点 | 118-122ºC | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Soluble MHC-II proteins promote suppressive activity in CD4+ T cells.
Immunology 144(1) , 158-69, (2014) Soluble MHCII (sMHCII) molecules are present in body fluids of healthy individuals and are considered to be involved in the maintenance of self tolerance, and are also related to various diseases. Their concentration increases during in vivo antigen-specific ... |
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Biological features of herpes simplex virus type 1 latency in mice according to experimental conditions and type of neurones.
Invest. Ophthalmol. Vis. Sci. 55(12) , 7761-74, (2014) To compare the biological patterns of viral transcripts during herpes simplex virus type 1 (HSV1) latent infection according to experimental conditions.Two types of murine models of HSV1 infection were used: the corneal scarification model, often used in stud... |
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Characterization of herpes simplex virus 2 primary microRNA Transcript regulation.
J. Virol. 89(9) , 4837-48, (2015) In order to understand factors that may influence latency-associated transcription and latency-associated transcript (LAT) phenotypes, we studied the expression of the herpes simplex virus 2 (HSV-2) LAT-associated microRNAs (miRNAs). We mapped the transcripti... |
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HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains.
Oncogene 34(3) , 334-45, (2015) The retroviral oncoprotein Tax from human T-cell leukemia virus type 1 (HTLV-1), an etiological factor that causes adult T-cell leukemia and lymphoma, has a crucial role in initiating T-lymphocyte transformation by inducing oncogenic signaling activation. We ... |
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The orientation of HIV-1 gp120 binding to the CD4 receptor differentially modulates CD4+ T cell activation.
J. Immunol. 194(2) , 637-49, (2015) Progressive quantitative and qualitative decline of CD4(+) T cell responses is one hallmark of HIV-1 infection and likely depends on several factors, including a possible contribution by the HIV-1 envelope glycoprotein gp120, which binds with high affinity to... |
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The BCR-ABL inhibitor ponatinib inhibits platelet immunoreceptor tyrosine-based activation motif (ITAM) signaling, platelet activation and aggregate formation under shear.
Thromb. Res. 135(1) , 155-60, (2014) Treatment of chronic myelogenous leukemia (CML) with the BCR-ABL tyrosine kinase inhibitor (TKI) imatinib significantly improves patient outcomes. As some patients are unresponsive to imatinib, next generation BCR-ABL inhibitors such as nilotinib have been de... |
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miR-20a inhibits TCR-mediated signaling and cytokine production in human naïve CD4+ T cells.
PLoS ONE 10(4) , e0125311, (2015) Upon TCR stimulation by peptide-MHC complexes, CD4+ T cells undergo activation and proliferation. This process will ultimately culminate in T-cell differentiation and the acquisition of effector functions. The production of specific cytokines by differentiate... |
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PP6 controls T cell development and homeostasis by negatively regulating distal TCR signaling.
J. Immunol. 194(4) , 1654-64, (2015) T cell development and homeostasis are both regulated by TCR signals. Protein phosphorylation and dephosphorylation, which are catalyzed by protein kinases and phosphatases, respectively, serve as important switches controlling multiple downstream pathways tr... |
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Subcellular localization and activation of ADAM proteases in the context of FasL shedding in T lymphocytes.
Mol. Immunol. 65(2) , 416-28, (2015) The "A Disintegrin And Metalloproteinases" (ADAMs) form a subgroup of the metzincin endopeptidases. Proteolytically active members of this protein family act as sheddases and govern key processes in development and inflammation by regulating cell surface expr... |
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The role of palmitoylation and transmembrane domain in sorting of transmembrane adaptor proteins.
J. Cell Sci. 129 , 95-107, (2016) Plasma membrane proteins synthesised at the endoplasmic reticulum are delivered to the cell surface via sorting pathways. Hydrophobic mismatch theory based on the length of the transmembrane domain (TMD) dominates discussion about determinants required for pr... |