N-CBZ-L-脯氨酸
N-CBZ-L-脯氨酸结构式
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常用名 | N-CBZ-L-脯氨酸 | 英文名 | Z-Pro-OH |
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| CAS号 | 1148-11-4 | 分子量 | 249.262 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 432.3±45.0 °C at 760 mmHg | |
| 分子式 | C13H15NO4 | 熔点 | 76-78ºC | |
| MSDS | 中文版 美版 | 闪点 | 215.3±28.7 °C |
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Prolidase is required for early trafficking events during influenza A virus entry.
J. Virol. 88(19) , 11271-83, (2014) Influenza A virus (IAV) entry is a multistep process that requires the interaction of the virus with numerous host factors. In this study, we demonstrate that prolidase (PEPD) is a cellular factor required by IAV for successful entry into target cells. PEPD w... |
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N-benzyloxycarbonyl-L-proline: an in vitro and in vivo inhibitor of prolidase.
Biochim. Biophys. Acta 1744(2) , 157-63, (2005) Prolidase deficiency (PD) is a recessive disorder of the connective tissue caused by mutations in the prolidase, a specific peptidase, cleaving the dipeptides with a C-terminal prolyl and hydroxyprolyl residue. PD is a complex syndrome characterized mainly by... |
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Proline prodrug of melphalan targeted to prolidase, a prodrug activating enzyme overexpressed in melanoma.
Pharm. Res. 24(7) , 1290-8, (2007) To determine the bioactivation and uptake of prolidase-targeted proline prodrugs of melphalan in six cancer cell lines with variable prolidase expression and to evaluate prolidase-dependence of prodrug cytotoxicity in the cell lines compared to that of the pa... |
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Prolidase-dependent regulation of TGF c and TGF β receptor expressions in human skin fibroblasts
Eur. J. Pharmacol. 649(1-3) , 115-9, (2010) Transforming growth factor beta 1 (TGF β1) is a protein that in most cells control proliferation and differentiation. One of the best characterized functions of TGF β1 is stimulation of collagen biosynthesis that may lead to tissue fibrosis. Several reports s... |
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Cytotoxicity of carbobenzoxy-protected amino acids.
In Vitro Cell. Dev. Biol. 28A(5) , 300-2, (1992)
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