1-(氨基甲基)-3,4-二氢-3-苯基-1H-2-苯并吡喃-5,6-二醇盐酸盐
1-(氨基甲基)-3,4-二氢-3-苯基-1H-2-苯并吡喃-5,6-二醇盐酸盐结构式
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常用名 | 1-(氨基甲基)-3,4-二氢-3-苯基-1H-2-苯并吡喃-5,6-二醇盐酸盐 | 英文名 | A-68930 hydrochloride |
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| CAS号 | 130465-39-3 | 分子量 | 307.77200 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C16H18ClNO3 | 熔点 | 250ºC | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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A-68930, a novel, potent dopamine D1 receptor agonist: a microstructural analysis of its effects on feeding and other behaviour in the rat.
Behav. Pharmacol. 5 , 210-218 , (1994) A-68930 [1R, 3S)-1-aminomethyl-5,6-dihydroxy-3-phenylisochroman HCI] is a novel, potent and selective dopamine D1 receptor agonist. Previous reports have shown that the selective D1 partial agonist, SK & F 38393, reduced food consumption in rats and mice. The... |
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Sedative effects of the dopamine D1 receptor agonist A 68930 on rat open-field behavior.
Neuroreport 11 , 1269-1279, (2000) The present results demonstrate sedative effects of the DA D1 receptor agonist A 68930 (0.9-15 micromol kg(-1), s.c.) on rat spontaneous locomotor activity in an open field. The effects were particularly strong, and dose-dependent, for the ambulatory activity... |
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A68930: a potent and specific agonist for the D-1 dopamine receptor.
Am. J. Hypertens. 3 , 40S-42S, (1990) A68930 (5,6-dihydroxy-3-phenyl-1-aminomethyl-isochroman) is a potent (EC50 = 2.5 nmol/L) partial agonist at the D-1 dopamine receptor. In contrast, A68930 is a much weaker agonist (EC50 = 3,920 nmol/L) at the D-2 dopamine receptor. The orientation of the 3-ph... |