射干苷
射干苷结构式
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常用名 | 射干苷 | 英文名 | tectoridin |
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| CAS号 | 611-40-5 | 分子量 | 462.404 | |
| 密度 | 1.6±0.1 g/cm3 | 沸点 | 798.1±60.0 °C at 760 mmHg | |
| 分子式 | C22H22O11 | 熔点 | 261.8-263.2ºC | |
| MSDS | 中文版 美版 | 闪点 | 279.7±26.4 °C |
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Tectorigenin inhibits IFN-gamma/LPS-induced inflammatory responses in murine macrophage RAW 264.7 cells.
Arch. Pharm. Res. 31(11) , 1447-56, (2008) Tectorigenin (Tg) and tectoridin (Td) are the major compounds isolated from the rhizomes of iridaceous plant Belamcanda chinensis which is well known as a chinese traditional medicine for the treatment of inflammatory diseases. In this study we investigated w... |
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Tectoridin, a poor ligand of estrogen receptor alpha, exerts its estrogenic effects via an ERK-dependent pathway.
Mol. Cells 27(3) , 351-7, (2009) Phytoestrogens are the natural compounds isolated from plants, which are structurally similar to animal estrogen, 17beta-estradiol. Tectoridin, a major isoflavone isolated from the rhizome of Belamcanda chinensis. Tectoridin is known as a phytoestrogen, howev... |
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Microbial transformation and bioactivation of isoflavones from Pueraria flowers by human intestinal bacterial strains.
J. Nat. Med. 63(3) , 254-60, (2009) The flowers from Pueraria, which are called Puerariae Flos, have been used since ancient times for recovery from alcohol intoxication. We elucidated the microbial transformation of the main isoflavones (1, 1a and 2) by using 29 commercially available human in... |
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Inhibitory activity of isoflavones of Pueraria flowers on nitric oxide production from lipopolysaccharide-activated primary rat microglia.
J. Asian Nat. Prod. Res. 11(6) , 471-81, (2009) Microglial activation plays an important role in alcohol-induced neuroinflammation. In search for natural medicines that may be of therapeutic potential for alcoholism, two new natural isoflavone glycosides, 6-hydroxybiochanin A-6,7-di-O-beta-d-glucopyranosid... |
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Antioxidant activities of isoflavones from the rhizomes of Belamcanda chinensis on carbon tetrachloride-induced hepatic injury in rats.
Arch. Pharm. Res. 27(2) , 184-8, (2004) The present study was carried out to clarify whether tectorigenin and tectoridin isolated from the rhizomes of Belamcanda chinensis (Iridaceae) inhibit hepatic damage induced by carbon tetrachloride (CCl4)-intoxication in rats by the experimental methods in v... |
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Passive cutaneous anaphylaxis-inhibitory action of tectorigenin, a metabolite of tectoridin by intestinal microflora.
Biol. Pharm. Bull. 27(7) , 1099-102, (2004) Tectoridin isolated from the flowers of Pueraria thunbergiana (Leguminosae) are metabolized to tectorigenin by human intestinal microflora. When tectoridin was orally administered to rats, tectorigenin, but not tectoridin, was detected in urine after beta-glu... |
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Identification of metabolites of tectoridin in-vivo and in-vitro by liquid chromatography-tandem mass spectrometry.
J. Pharm. Pharmacol. 60(6) , 709-16, (2008) In this work, liquid chromatography-electrospray ionization tandem ion-trap mass spectrometry (LC-MS(n)) was used to investigate the in-vivo and in-vitro metabolism of tectoridin. After oral administration of a single dose (100 mg kg(-1)) of tectoridin to hea... |
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Determination of tectoridin in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies.
Biomed. Chromatogr. 23(7) , 754-8, (2009) A simple, specific and sensitive HPLC method with UV detection was developed and validated for the determination of tectoridin in rat plasma for the first time. Chromatographic separation was performed on a Welchrom C(18) column (150 x 4.6 mm, i.d., 5 microm)... |
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Polyphenolic compounds from callus cultures of Iris pseudacorus.
Nat. Prod. Commun. 8(10) , 1419-20, (2013) A callus culture of Iris pseudacorus L. (Iridaceae) was established from plant leaves using a modified Murashige and Skoog medium. A derivative of cinnamic acid (lavandoside) (1), a neolignan (dehydrodiconiferyl alcohol-4-O-beta-D-glucopyranoside) (2) as well... |
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Purification and structure determination of gelatinase and collagenase inhibitors from Viola patrinii fermentation extracts.
Immunopharmacol. Immunotoxicol. 32(4) , 614-6, (2010) Investigation of collagenase and gelatinase inhibitory natural components afforded two isoflavonoids. Two isoflavonoids, tectorigenin-7-O-β-D-glucoside (1) and luteolin-7-O-β-D-glucuronopyranoside (2), were isolated from ethyl acetate fraction of Viola patrin... |