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VU 0364849

VU 0364849结构式
VU 0364849结构式
品牌特惠专场
常用名 VU 0364849 英文名 VU 0364849
CAS号 1206711-14-9 分子量 451.520
密度 1.3±0.1 g/cm3 沸点 N/A
分子式 C27H25N5O2 熔点 N/A
MSDS 美版 闪点 N/A

Small molecule antagonist of the bone morphogenetic protein type I receptors suppresses growth and expression of Id1 and Id3 in lung cancer cells expressing Oct4 or nestin.

Mol. Cancer 12(1) , 129, (2013)

Bone morphogenetic proteins (BMP) are embryonic morphogens that are aberrantly expressed in lung cancer. BMPs mediate cell fate decisions and self-renewal of stem cells, through transcription regulation of inhibitor of differentiation protein/DNA binding prot...