COMPLEMENT C8 来源于人类血清
COMPLEMENT C8 来源于人类血清结构式
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常用名 | COMPLEMENT C8 来源于人类血清 | 英文名 | C8, HUMAN |
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| CAS号 | 80295-58-5 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | N/A | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A |
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Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J. Biol. Chem. 286 , 17585-17592, (2011) C8 is one of five complement proteins that assemble on bacterial membranes to form the lethal pore-like "membrane attack complex" (MAC) of complement. The MAC consists of one C5b, C6, C7, and C8 and 12-18 molecules of C9. C8 is composed of three genetically d... |
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Structure of human complement C8, a precursor to membrane attack.
J. Mol. Biol. 405 , 325-330, (2011) Complement component C8 plays a pivotal role in the formation of the membrane attack complex (MAC), an important antibacterial immune effector. C8 initiates membrane penetration and coordinates MAC pore formation. High-resolution structures of C8 subunits hav... |
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Functional studies of the MACPF domain of human complement protein C8alpha reveal sites for simultaneous binding of C8beta, C8gamma, and C9.
Biochemistry 45 , 5290-5296, (2006) Human C8 is one of five components of the membrane attack complex of complement (MAC). It contains three subunits (C8alpha, C8beta, C8gamma) arranged as a disulfide-linked C8alpha-gamma dimer that is noncovalently associated with C8beta. C8alpha, C8beta, and ... |