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HUMAN BETACELLULIN

HUMAN BETACELLULIN结构式
HUMAN BETACELLULIN结构式
品牌特惠专场
常用名 HUMAN BETACELLULIN 英文名 HUMAN BETACELLULIN
CAS号 163150-12-7 分子量 N/A
密度 N/A 沸点 N/A
分子式 N/A 熔点 N/A
MSDS 美版 闪点 N/A

Transplantation of betacellulin-transduced islets improves glucose intolerance in diabetic mice.

Exp. Mol. Med. 46 , e98, (2014)

Type 1 diabetes is an autoimmune disease caused by permanent destruction of insulin-producing pancreatic β cells and requires lifelong exogenous insulin therapy. Recently, islet transplantation has been developed, and although there have been significant adva...

Betacellulin activates the epidermal growth factor receptor and erbB-4, and induces cellular response patterns distinct from those stimulated by epidermal growth factor or neuregulin-beta.

Oncogene 12 , 345, (1996)

Betacellulin is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the erbB gene family (erbB-1/epidermal growth factor receptor (EGFR), neu/erbB-2/HER2, er...

Immunohistochemical localization of betacellulin, a new member of the EGF family, in normal human pancreas and islet tumor cells.

Endocrine J. 46 , 755-764, (1999)

Betacellulin (BTC) purified from mouse beta cell tumor (betaTC-3) is a new member of the epidermal growth factor (EGF) family which can bind receptor tyrosine kinase, EGF receptor (erbB1) and erbB4. It has been demonstrated that proBTC mRNA was abundantly exp...

Expression of the c-erbB-3/HER-3 and c-erbB-4/HER-4 growth factor receptors and their ligands, neuregulin-1 alpha, neuregulin-1 beta, and betacellulin, in normal endometrium and endometrial cancer.

Clin. Cancer Res. 5 , 2877-2883, (1999)

The objective of this study was to determine the immunohistochemical expression of the c-erbB-3 and c-erbB-4 growth factor receptors and their principal ligands, the neuregulins and betacellulin, in normal endometrium and determine whether there was evidence ...