Peptidylprolyl isomerase
Peptidylprolyl isomerase结构式
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常用名 | Peptidylprolyl isomerase | 英文名 | Peptidylprolyl isomerase |
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| CAS号 | 95076-93-0 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | N/A | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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[Determination of enzymatic catalysis for the cis-trans-isomerization of peptide binding in proline-containing peptides].
Biomed. Biochim. Acta 43 , 1101-1111, (1984) The rates of cis to trans interconversion of Glt-(Ala)n-Pro-Phe-4-nitroanilides (n = 1-3) were estimated by means of a two-step process with chymotrypsin as the trans-substrate cleaving activity. By the aid of this system, pig kidney and several other tissues... |
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Structural basis for protein antiaggregation activity of the trigger factor chaperone.
Science 344(6184) , 1250494, (2014) Molecular chaperones prevent aggregation and misfolding of proteins, but scarcity of structural data has impeded an understanding of the recognition and antiaggregation mechanisms. We report the solution structure, dynamics, and energetics of three trigger fa... |
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Biochemistry. Trigger factor flexibility.
Science 344(6184) , 590-1, (2014)
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Elastin binding protein and FKBP65 modulate in vitro self-assembly of human tropoelastin.
Biochemistry 52(44) , 7731-41, (2013) Elastin is a protein that provides the unusual properties of extensibility and elastic recoil to tissues. Assembly of polymeric elastin into its final architecture in the extracellular matrix involves both self-aggregation properties of its monomeric precurso... |
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Immunophilins control T lymphocyte adhesion and migration by regulating CrkII binding to C3G.
J. Immunol. 193(8) , 3966-77, (2014) Crk adaptor proteins are key players in signal transduction from a variety of cell surface receptors. CrkI and CrkII, the two alternative spliced forms of CRK, possess an N-terminal Src homology 2 domain, followed by a Src homology 3 (SH3) domain, whereas Crk... |
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Pin1 is required for ultraviolet A-stimulated cyclooxygenase-2 induction in mouse epidermal cells
Cancer Lett. 335(1) , 31-40, (2013) Highlights ► Pin1 and COX-2 are frequently overexpressed in most cancer cell types and plays an important role in oncogenesis. ► We studied whether exposure of epidermal cells to UVA affects COX-2 expression and the possible involvement of Pin1 activation. ► ... |
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Inhibition of the mitochondrial Hsp90 chaperone network: a novel, efficient treatment strategy for cancer?
Cancer Lett. 333(2) , 133-46, (2013) Research has shown that cancer cells exhibit multiple deregulated pathways, involving proliferation, migration and cell death. Heat-shock-proteins have evolved as "central regulators" and are implicated in the modulation of these pathways and in organelle-spe... |
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Identification of FkpA as a key quality control factor for the biogenesis of outer membrane proteins under heat shock conditions.
J. Bacteriol. 196(3) , 672-80, (2014) The outer membrane proteins (OMPs) of Gram-negative bacterial cells, as well as the mitochondrion and chloroplast organelles, possess unique and highly stable β-barrel structures. Biogenesis of OMPs in Escherichia coli involves such periplasmic chaperones as ... |
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An intramolecular chaperone inserted in bacteriophage P22 coat protein mediates its chaperonin-independent folding.
J. Biol. Chem. 288(47) , 33772-83, (2013) The bacteriophage P22 coat protein has the common HK97-like fold but with a genetically inserted domain (I-domain). The role of the I-domain, positioned at the outermost surface of the capsid, is unknown. We hypothesize that the I-domain may act as an intramo... |
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FKBP5 and attention bias for threat: associations with hippocampal function and shape.
JAMA Psychiatry 70(4) , 392-400, (2013) The FKBP5 gene product regulates glucocorticoid receptor (GR) sensitivity and hypothalamic-pituitary-adrenal axis functioning and has been associated with many stress-related psychiatric disorders. The study of intermediate phenotypes, such as emotion-process... |