非格司亭
非格司亭结构式
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常用名 | 非格司亭 | 英文名 | FILGRASTIM |
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| CAS号 | 121181-53-1 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | W99 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A |
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Technical advance: ascorbic acid induces development of double-positive T cells from human hematopoietic stem cells in the absence of stromal cells.
J. Leukoc. Biol. 96(6) , 1165-75, (2014) The efficacy of donor HSCT is partly reduced as a result of slow post-transplantation immune recovery. In particular, T cell regeneration is generally delayed, resulting in high infection-related mortality in the first years post-transplantation. Adoptive tra... |
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Dose-adjusted EPOCH-rituximab therapy in primary mediastinal B-cell lymphoma.
N. Engl. J. Med. 368(15) , 1408-16, (2013) Primary mediastinal B-cell lymphoma is a distinct subtype of diffuse large-B-cell lymphoma that is closely related to nodular sclerosing Hodgkin's lymphoma. Patients are usually young and present with large mediastinal masses. There is no standard treatment, ... |
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Cladribine in the treatment of acute myeloid leukemia.
Leuk. Res. 38(4) , 425-7, (2014)
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Cladribine, cytarabine, filgrastim, and mitoxantrone (CLAG-M) compared to standard induction in acute myeloid leukemia from myelodysplastic syndrome after azanucleoside failure
Leuk. Res. 38(4) , 443-6, (2014) For patients with acute myeloid leukemia from antecedent myelodysplastic syndrome particularly after azanucleoside treatment failure, outcome is poor. Here, we conducted a case-control study in these patients to compare the efficacy of CLAG-M induction (28 pa... |
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Fractionated gemtuzumab ozogamicin and standard dose cytarabine produced prolonged second remissions in patients over the age of 55 years with acute myeloid leukemia in late first relapse.
Am. J. Hematol. 89(4) , 399-403, (2014) Gemtuzumab ozogamicin (fGO), a humanized anti-CD33 monoclonal antibody linked to calicheamicin in combination with intensive chemotherapy gives high response rates in adult acute myeloid leukemia (AML) patients in relapse. However, reduced intensity chemother... |
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Nonmyeloablative HLA-matched sibling allogeneic hematopoietic stem cell transplantation for severe sickle cell phenotype.
JAMA 312(1) , 48-56, (2014) Myeloablative allogeneic hematopoietic stem cell transplantation (HSCT) is curative for children with severe sickle cell disease, but toxicity may be prohibitive for adults. Nonmyeloablative transplantation has been attempted with degrees of preparative regim... |
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Acute colchicine intoxication complicated with extramedullary hematopoiesis due to filgrastim in a child.
J. Pediatr. Hematol. Oncol. 36(7) , e460-2, (2014) Colchicine is a widely used alkaloid extract in children and adults for standard therapy and prophylaxis for amyloid deposition in different rheumatologic disorders. Colchicine intoxication is a rare but severe complication. The aim of this study was to repor... |
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Granulocyte colony-stimulating factor with or without stem cell factor extends time to premature ovarian insufficiency in female mice treated with alkylating chemotherapy.
Fertil. Steril. 99(7) , 2045-54.e3, (2013) To examine gonadal protective properties of granulocyte colony-stimulating factor (G-CSF) alone or in combination with stem cell factor (SCF) in female mice treated with high-dose alkylating chemotherapy.Experimental laboratory animal study.Tertiary care acad... |
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Clozapine re-challenge under the cover of Filgrastim.
J. Postgrad. Med. 59(1) , 54-5, (2013) Rechallenge with clozapine, despite a history of clozapine-induced neutropenia is considered in patients with a good response to the drug in the past, for whom no other treatments are effective, and in cases where the risks of withholding treatment are greate... |
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The ability of filgrastim to mitigate mortality following LD50/60 total-body irradiation is administration time-dependent.
Health Phys. 106(1) , 39-47, (2014) The identification of the optimal administration schedule for an effective medical countermeasure is critical for the effective treatment of individuals exposed to potentially lethal doses of radiation. The efficacy of filgrastim (Neupogen®), a potential medi... |