pTH-Related Protein (1-34) amide (human, mouse, rat) trifluoroacetate salt
pTH-Related Protein (1-34) amide (human, mouse, rat) trifluoroacetate salt结构式
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常用名 | pTH-Related Protein (1-34) amide (human, mouse, rat) trifluoroacetate salt | 英文名 | pTH-Related Protein (1-34) amide (human, mouse, rat) trifluoroacetate salt |
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| CAS号 | 112955-31-4 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C180H288N58O47 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Parathyroid hormone-related protein of malignancy: active synthetic fragments.
Science 238 , 1568, (1967) Peptides corresponding to the amino-terminal region of the parathyroid hormone-related protein (PTHrP) of humoral hypercalcemia of malignancy were synthesized. A 34-amino acid peptide, PTHrP(1-34), was two to four times more potent than bovine or human PTH(1-... |
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Parathyroid hormone-related peptide stimulates proliferation of highly tumorigenic human SV40-immortalized breast epithelial cells.
J. Bone Miner Res. 15 , 2129-2139, (2000) Parathyroid hormone-related protein (PTHrP) is the main mediator of humoral hypercalcemia of malignancy (HHM) and it is produced by many tumors, including breast cancers. Breast epithelial cells as well as breast cancer tumors and cell lines have been reporte... |
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Etomidate is associated with mortality and adrenal insufficiency in sepsis: a meta-analysis*.
Science 238 , 1566, (1987) To evaluate the effects of single-dose etomidate on the adrenal axis and mortality in patients with severe sepsis and septic shock.A systematic review of randomized controlled trials and observational studies with meta-analysis.Literature search of EMBASE, Me... |
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Tumor necrosis factor enhances parathyroid hormone-related protein-induced hypercalcemia and bone resorption without inhibiting bone formation in vivo.
Cancer Res. 57 , 3194-3199, (1997) Humoral hypercalcemia of malignancy results from the effects of tumor-produced factors on bone, kidney, and intestine that disrupt normal calcium homeostasis. Although parathyroid hormone-related protein (PTHrP) is a major mediator of the syndrome, tumors als... |
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Effects of transforming growth factor-alpha on parathyroid hormone- and parathyroid hormone-related protein-mediated bone resorption and adenylate cyclase stimulation in vitro.
Domest. Anim. Endocrinol. 8 , 499-507, (1991) The effects of transforming growth factor-alpha (TGF alpha) were determined on the ability of parathyroid hormone (PTH) or parathyroid hormone-related protein (PTHrP) to stimulate bone resorption and adenylate cyclase in vitro. Bovine PTH-(1-34) and human PTH... |
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Characterization of parathyroid hormone/parathyroid hormone-related protein receptor and signaling in hypercalcemic Walker 256 tumor cells.
J. Endocrinol. 166 , 11-20, (2000) Parathyroid hormone (PTH)-related protein (PTHrP) is the main factor responsible for humoral hypercalcemia of malignancy. Both PTH and PTHrP bind to the common type I PTH/PTHrP receptor (PTHR), thereby activating phospholipase C and adenylate cyclase through ... |
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Parathyroid hormone-related peptide and primary hyperparathyroidism. Testini M, Gurrado A, et al.
Front. Biosci. 2 , 299-312, (2010)
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