聚脱氧核糖核酸
聚脱氧核糖核酸结构式
|
常用名 | 聚脱氧核糖核酸 | 英文名 | POLYDEOXYADENYLIC-THYMIDYLIC ACID SODIUM SALT |
|---|---|---|---|---|
| CAS号 | 86828-69-5 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | N/A | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
|
Unbiased modifier screen reveals that signal strength determines the regulatory role murine TLR9 plays in autoantibody production.
J. Immunol. 194(8) , 3675-86, (2015) The autoimmune disease systemic lupus erythematosus has a complex environmental and multifactorial genetic basis. Genome-wide association studies have recently identified numerous disease-associated polymorphisms, but it remains unclear in which cells and dur... |
|
|
PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function.
Mol. Cell. Biol. 35(10) , 1741-53, (2015) Insults to cellular health cause p53 protein accumulation, and loss of p53 function leads to tumorigenesis. Thus, p53 has to be tightly controlled. Here we report that the BTB/POZ domain transcription factor PATZ1 (MAZR), previously known for its transcriptio... |
|
|
Conformational variability of poly(dA-dT).poly(dA-dT) and some other deoxyribonucleic acids includes a novel type of double helix.
J. Biomol. Struct. Dyn. 3 , 67-83, (1985) The article reviews data indicating that poly(dA-dT).poly(dA-dT) is able of adopting three distinct double helical structures in solution, of which only the A form conforms to classical notions. The other two structures have dinucleotides as double helical re... |
|
|
[Cu(o-phthalate)(phenanthroline)] Exhibits Unique Superoxide-Mediated NCI-60 Chemotherapeutic Action through Genomic DNA Damage and Mitochondrial Dysfunction.
ACS Chem. Biol. 11 , 159-71, (2016) The in cellulo catalytic production of reactive oxygen species (ROS) by copper(II) and iron(II) complexes is now recognized as a major mechanistic model in the design of effective cytotoxins of human cancer. The developmental complex, [Cu(o-phthalate)(1,10-ph... |
|
|
Circular dichroism of polynucleotides: Interactions of NiCl2 with poly(dA-dT).poly(dA-dT) and poly(dG-dC).poly(dG-dC) in a water-in-oil microemulsion.
Chirality 20 , 951-960, (2008) The thermal behavior of the synthetic, high molecular weight, double stranded polynucleotides poly(dA-dT).poly(dA-dT) [polyAT] and poly(dG-dC).poly(dG-dC) [polyGC] solubilized in the aqueous core of the quaternary water-in-oil cationic microemulsion CTAB|n-pe... |
|
|
Interaction of the alternating double stranded copolymer poly(dA-dT) x poly(dA-dT) with NiCl(2) and CdCl(2): solution behavior.
J. Biomol. Struct. Dyn. 25 , 77-84, (2007) The thermal denaturation of the synthetic high molecular weight double stranded polynucleotide poly(dA-dT) x poly(dA-dT) has been studied in aqueous buffered solution (Tris 1.0 mM; pH 7.8+/-0.2) in the presence of increasing concentrations of either Ni(2+) (b... |