甘露聚糖
甘露聚糖结构式
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常用名 | 甘露聚糖 | 英文名 | Mannan from Saccharomyces cerevisiae |
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| CAS号 | 9036-88-8 | 分子量 | 666.578 | |
| 密度 | 1.8±0.1 g/cm3 | 沸点 | 1030.9±65.0 °C at 760 mmHg | |
| 分子式 | C24H42O21 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 577.3±34.3 °C |
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Functional assessment of mouse complement pathway activities and quantification of C3b/C3c/iC3b in an experimental model of mouse renal ischaemia/reperfusion injury
J. Immunol. Methods 419 , 25-34, (2015) The complement system is an essential component of our innate immunity, both for the protection against infections and for proper handling of dying cells. However, the complement system can also contribute to tissue injury and inflammatory responses. In view ... |
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A Metalloproteinase Mirolysin of Tannerella forsythia Inhibits All Pathways of the Complement System.
J. Immunol. 195 , 2231-40, (2015) Recent reports focusing on virulence factors of periodontal pathogens implicated proteinases as major determinants of remarkable pathogenicity of these species, with special emphasis on their capacity to modulate complement activity. In particular, bacteria-m... |
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Genetically engineered fusion of MAP-1 and factor H domains 1-5 generates a potent dual upstream inhibitor of both the lectin and alternative complement pathways.
FASEB J. 29 , 4945-55, (2015) Inhibition of the complement cascade has emerged as an option for treatment of a range of diseases. Mannose-binding lectin/ficolin/collectin-associated protein (MAP-1) is a pattern recognition molecule (PRM)-associated inhibitor of the lectin pathway. The cen... |
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M. leprae components induce nerve damage by complement activation: identification of lipoarabinomannan as the dominant complement activator.
Acta Neuropathol. 129(5) , 653-67, (2015) Peripheral nerve damage is the hallmark of leprosy pathology but its etiology is unclear. We previously identified the membrane attack complex (MAC) of the complement system as a key determinant of post-traumatic nerve damage and demonstrated that its inhibit... |
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Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis.
PLoS ONE 6(1) , e15723, (2011) The ten mouse and six human members of the Schlafen (Slfn) gene family all contain an AAA domain. Little is known of their function, but previous studies suggest roles in immune cell development. In this report, we assessed Slfn regulation and function in mac... |
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Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis.
J. Clin. Invest. 126 , 1093-108, (2016) In extrapulmonary tuberculosis, the most common site of infection is within the lymphatic system, and there is growing recognition that lymphatic endothelial cells (LECs) are involved in immune function. Here, we identified LECs, which line the lymphatic vess... |
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Histidine-rich glycoprotein protects from systemic Candida infection.
PLoS Pathog. 4(8) , e1000116, (2008) Fungi, such as Candida spp., are commonly found on the skin and at mucosal surfaces. Yet, they rarely cause invasive infections in immunocompetent individuals, an observation reflecting the ability of our innate immune system to control potentially invasive m... |
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Nonopsonic uptake of Mycobacterium avium complex by human monocytes and alveolar macrophages.
J. Lab. Clin. Med. 119 , 772-81, (1992) The uptake of Mycobacterium avium complex (MAC) microorganisms by human peripheral blood monocytes (PBMs) and alveolar macrophages (AMs) is not well understood. We have previously shown, under opsonic conditions, that humoral factors are important in mediatin... |
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New lectins from bulbs of Croccus sativum.
Biol. Pharm. Bull. 16 , 978-81, (1993) Four isolectins were isolated from bulbs of Croccus sativum (saffron), using affinity chromatography on mannan-Sepharose 4B, gel filtration and ion-exchange column chromatography in the presence of 8 M urea. The relative molecular masses of these lectins were... |
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A comparison of yeast mannans and phosphomannans by acetolysis.
Biochemistry 7 , 1855-63, (1968)
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