纤维蛋白原
纤维蛋白原结构式
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常用名 | 纤维蛋白原 | 英文名 | Fibrinogen (Bovine) |
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| CAS号 | 9001-32-5 | 分子量 | 236.739 | |
| 密度 | 1.8±0.1 g/cm3 | 沸点 | 186.8±0.0 °C at 760 mmHg | |
| 分子式 | C2Cl6 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 61.3±15.8 °C |
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Is dilutional coagulopathy induced by different colloids reversible by replacement of fibrinogen and factor XIII concentrates?
Anesth. Analg. 117(5) , 1063-71, (2013) In this in vitro trial, we assessed the effect on blood coagulation of 60% dilution with different colloids and investigated reversibility by replacement of factor XIII (F XIII), fibrinogen, and the combination of fibrinogen and F XIII.Using the blood of 12 v... |
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A re-assessment of long distance growth and connectivity of neural stem cells after severe spinal cord injury.
Exp. Neurol. 257 , 186-204, (2014) As part of the NIH "Facilities of Research Excellence-Spinal Cord Injury" project to support independent replication, we repeated key parts of a study reporting robust engraftment of neural stem cells (NSCs) treated with growth factors after complete spinal c... |
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Novel thrombolytic protease from edible and medicinal plant Aster yomena (Kitam.) Honda with anticoagulant activity: purification and partial characterization.
J. Biosci. Bioeng. 118(4) , 372-7, (2014) A thrombolytic protease named kitamase possessing anticoagulant property was purified from edible and medicinal plant Aster yomena (Kitam.) Honda. Kitamase showed a molecular weight of 50 kDa by SDS-PAGE and displayed a strong fibrin zymogram lysis band corre... |
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The regulatory T cell effector molecule fibrinogen-like protein 2 is necessary for the development of rapamycin-induced tolerance to fully MHC-mismatched murine cardiac allografts.
Immunology 144(1) , 91-106, (2015) Therapies that promote tolerance in solid organ transplantation will improve patient outcomes by eliminating the need for long-term immunosuppression. To investigate mechanisms of rapamycin-induced tolerance, C3H/HeJ mice were heterotopically transplanted wit... |
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Effects of fibrinogen concentration on fibrin glue and bone powder scaffolds in bone regeneration.
J. Biosci. Bioeng. 118(4) , 469-75, (2014) Fibrin polymers are widely used in the tissue engineering field as biomaterials. Although numerous researchers have studied the fabrication of scaffolds using fibrin glue (FG) and bone powder, the effects of varied fibrinogen content during the fabrication of... |
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FIBTEM PLUS provides an improved thromboelastometry test for measurement of fibrin-based clot quality in cardiac surgery patients.
Anesth. Analg. 117(5) , 1054-62, (2013) The viscoelastic functional fibrinogen (FF) and FIBTEM assays measure the contribution of fibrin to clot strength. Inhibition of platelet function is a necessary precondition for these tests to work. We investigated a novel test for measuring fibrin-based clo... |
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In vitro effects of proteases in human pancreatic juice on stability of liquid and carrier-bound fibrin sealants.
Br. J. Surg. 100(11) , 1498-504, (2013) Fibrin sealants are used in pancreatic surgery to prevent leakage of pancreatic fluid and reduce associated complications. The efficacy of this approach is unclear.Fibrin clots were generated in vitro from two commercially available liquid fibrin sealants (Ti... |
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Does topology drive fiber polymerization?
Biochemistry 53(49) , 7824-34, (2014) We have developed new procedures to examine the early steps in fibrin polymerization. First, we isolated fibrinogen monomers from plasma fibrinogen by gel filtration. Polymerization of fibrinogen monomers differed from that of plasma fibrinogen. The formation... |
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Genetic polymorphisms influencing total and γ' fibrinogen levels and fibrin clot properties in Africans.
Br. J. Haematol. 168(1) , 102-12, (2015) Inter-ethnic variation in fibrinogen levels is hypothesized to be the result of differences in genetic background. No information is available regarding the contribution of genetics to fibrinogen γ' in Africans. Only limited information is available regarding... |
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Associations between three specific a-cellular measures of the oxidative potential of particulate matter and markers of acute airway and nasal inflammation in healthy volunteers.
Occup. Environ. Med. 72(1) , 49-56, (2015) We evaluated associations between three a-cellular measures of the oxidative potential (OP) of particulate matter (PM) and acute health effects.We exposed 31 volunteers for 5 h to ambient air pollution at five locations: an underground train station, two traf... |