3-甲基黄酮-8-甲酸
3-甲基黄酮-8-甲酸结构式
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常用名 | 3-甲基黄酮-8-甲酸 | 英文名 | 3-methylflavone-8-carboxylic acid |
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| CAS号 | 3468-01-7 | 分子量 | 280.28 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 485.1±45.0 °C at 760 mmHg | |
| 分子式 | C17H12O4 | 熔点 | 234-236°C | |
| MSDS | N/A | 闪点 | 183.3±22.2 °C |
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Pharmacological activities of the main metabolite of flavoxate 3-methylflavone-8-carboxylic acid.
Arzneimittelforschung 38(3) , 379-82, (1988) The pharmacological properties of 3-methylflavone-8-carboxylic acid (MFCA), the main metabolite of flavoxate, have been studied in vitro and in vivo. MFCA did not display antispasmodic activity on isolated organs contractions induced by histamine, acetylcholi... |
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Determination of 3-methylflavone-8-carboxylic acid, the main metabolite of flavoxate, in human urine by capillary electrophoresis with direct injection.
J. Chromatogr. A. 612(2) , 287-94, (1993) The effects of tetraalkylammonium salts and sodium dodecyl sulphate on the migration behaviour of human urinary components and other negatively charged or neutral solutes were investigated. The sulphate acted mainly on hydrophobic and positively charged subst... |
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Antispasmodic effects of flavoxate, MFCA, and REC 15/2053 on smooth muscle of human prostate and urinary bladder.
Urology 37(4) , 390-4, (1991) The antispasmodic effects of the flavone compounds flavoxate hydrochloride, 3-methylflavone carboxylic acid (MFCA), and REC 15/2053 (and in the case of the detrusor, oxybutynin), on the human detrusor, prostatic adenoma, prostatic capsule, and bladder neck, w... |
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Development of a high-performance liquid chromatographic method for bioequivalence study of flavoxate tablets.
J. Chromatogr. B. Biomed. Sci. Appl. 751(1) , 79-86, (2001) An improved HPLC method was developed for the concentration determination of the metabolite of flavoxate, 3-methyl-flavone-8-carboxylic acid (MFCA), in plasma in an attempt to compare two flavoxate tablet formulations. This HPLC method was validated by examin... |
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Liquid chromatographic fingerprint of 3-methylflavone-8-carboxylic acid established for its synthesis control analysis
Talanta 77(5) , 1573-8, (2009) A high-performance liquid chromatographic method was proposed for the separation of relative impurities in industrial 3-methylflavone-8-carboxylic acid (MFCA) and its intermediate methyl 3-propionylsalicylate (MPS). Benzoic acid (BA), MPS, 6-chloro-3-methylfl... |
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Molecularly imprinted polymer for selective extraction of 3-methylflavone-8-carboxylic acid from human urine followed by its determination using zwitterionic hydrophilic interaction liquid chromatography.
J. Sep. Sci. 34(22) , 3265-71, (2011) A novel water-compatible molecularly imprinted SPE combined with zwitterionic hydrophilic interaction liquid chromatography method for selective extraction and determination of 3-methylflavone-8-carboxylic acid (MFA), the main active metabolite of flavoxate i... |
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High-performance liquid chromatographic determination of flavoxate hydrochloride and its hydrolysis product.
Drug Dev. Ind. Pharm. 34(12) , 1311-22, (2008) Liquid chromatographic method was presented for the determination of flavoxate hydrochloride (FX) and its hydrolysis product. The method was based on high-performance liquid chromatographic (HPLC) separation of FX from its hydrolysis product on CN column usin... |