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醋酸特立帕肽

醋酸特立帕肽结构式
醋酸特立帕肽结构式
品牌特惠专场
常用名 醋酸特立帕肽 英文名 pTH (1-34) (human) acetate salt
CAS号 52232-67-4 分子量 4177.77000
密度 N/A 沸点 N/A
分子式 C181H291N55O51S2 熔点 N/A
MSDS 美版 闪点 N/A

Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA.

Arthritis. Res. Ther. 17 , 315, (2015)

Osteoarthritis (OA) is a leading cause of disability, but despite the high unmet clinical need and extensive research seeking dependable therapeutic interventions, no proven disease-modifying treatment for OA is currently available. Due to the close interacti...

Protein chemical synthesis by serine and threonine ligation.

Proc. Natl. Acad. Sci. U. S. A. 110(17) , 6657-62, (2013)

An efficient method has been developed for the salicylaldehyde ester-mediated ligation of unprotected peptides at serine (Ser) or threonine (Thr) residues. The utility of this peptide ligation approach has been demonstrated through the convergent syntheses of...

Double and quadruple tetracycline labeling of bone: impact of the label itself.

J. Bone Miner Res. 28(1) , 222-3, (2013)

Assessing the effect of baseline status of serum bone turnover markers and vitamin D levels on efficacy of teriparatide 20 μg/day administered subcutaneously in Japanese patients with osteoporosis.

J. Bone Miner. Metab. 31(2) , 199-205, (2013)

In this previously reported multicenter study, teriparatide 20 μg/day was administered to elderly Japanese subjects (93 % female; median age 70 years) with osteoporosis and at high risk of fracture during a 12-month, randomized, double-blind, placebo-controll...

Association of teriparatide adherence and persistence with clinical and economic outcomes in Medicare Part D recipients: a retrospective cohort study.

BMC Musculoskelet. Disord. 14 , 4, (2013)

Improper medication adherence is associated with increased morbidity, healthcare costs, and fracture risk among patients with osteoporosis. The objective of this study was to evaluate the healthcare utilization patterns of Medicare Part D beneficiaries newly ...

The cost effectiveness of teriparatide as a first-line treatment for glucocorticoid-induced and postmenopausal osteoporosis patients in Sweden.

BMC Musculoskelet. Disord. 13 , 213, (2012)

This paper presents the model and results to evaluate the use of teriparatide as a first-line treatment of severe postmenopausal osteoporosis (PMO) and glucocorticoid-induced osteoporosis (GIOP). The study's objective was to determine if teriparatide is cost ...

Parathyroid hormone reverses radiation induced hypovascularity in a murine model of distraction osteogenesis.

Bone 56(1) , 9-15, (2013)

Radiation treatment results in a severe diminution of osseous vascularity. Intermittent parathyroid hormone (PTH) has been shown to have an anabolic effect on osteogenesis, though its impact on angiogenesis remains unknown. In this murine model of distraction...

Using common random numbers in health care cost-effectiveness simulation modeling.

Health Serv. Res. 48(4) , 1508-25, (2013)

To identify the problem of separating statistical noise from treatment effects in health outcomes modeling and analysis. To demonstrate the implementation of one technique, common random numbers (CRNs), and to illustrate the value of CRNs to assess costs and ...

Case report: Teriparatide treatment in a case of severe pregnancy -and lactation- associated osteoporosis.

Hormones (Athens.) 11(4) , 495-500, (2012)

Pregnancy- and lactation-associated osteoporosis (PLO) is an uncommon disease. The majority of cases are seen in the third trimester or early post-partum in primagravid women and the prominent clinical feature of PLO is severe and prolonged back pain and heig...

Serum undercarboxylated osteocalcin level increases with 48 weeks of teriparatide treatment in pre-treated elderly rheumatoid arthritis patients who use anti-resorptive drugs.

J. Endocrinol. Invest. 35(9) , 796-9, (2012)

The serum undercarboxylated osteocalcin (ucOC) level, a biochemical bone marker of vitamin K insufficiency, is often affected by anti-osteoporosis drugs. There have been no reports regarding the relationship between ucOC and teriparatide.We conducted a prospe...